[#1999-04] Activity of Edible Mushrooms Against the Growth of Human T4 Leukemic Cancer Cells, HeLa Cervical Cancer Cells and Plasmodium falciparum, A. Lovy et al.

 Activity of Edible Mushrooms Against the Growth of Human T4 Leukemic Cancer Cells, HeLa Cervical Cancer Cells and Plasmodium falciparum

Lovy, A(a), Knowles, B(b), Labbe, R, Nolan(c), L(b)

a) Institute of Biological Chemistry, Washington State University, b) Department of Environmental Health Sciences, University of Massachusetts, c) Food Science Department, University of Massachusetts

Several edible Hymenomycete mushroom species have been screened as possible inhibitors of human T4 leukemic cancer cells, HeLa cervical cancer cells, Plasmodium falciparum (a pyrimethamine resistant malarial parasite), and six pathogenic microorganisms. Grifola frondosa ( maitake ), Ganoderma lucidum, Lentinula edodes, and Laetiporus sulphurues demonstrated activity against human T4 leukemic cancer cells. Grifola frondosa, Ganoderma lucidum, Lentinula edodes and Lentinula auranticacum demonstrated activity against HeLa cervical cancer cells. Polyporus umbellatus, Russula xerampelina, Ganoderma lucidum, Trametes versicolor, Lentinula aurantiacum, Laetiporus sulphureus, Boletus variipes, Boletus queletii, Grifola frondosa and Lentinula edodes demonstrated activity against Plasmodium falciparum. No activity was observed against the pathogenic microorganisms.