Abstract An entomopathogenic fungus, Cordyceps sp. has been known to have numerous pharmacological and therapeutic implications, especially, in terms of human health making it a suitable candidate for ethno-pharmacological
use. Main constituent of the extract derived from this fungus comprises a novel bio-metabolite called as Cordycepin
(30deoxyadenosine) which has a very potent anti-cancer, antioxidant and anti-inflammatory activities. The current review
discusses about the broad spectrum potential of Cordycepin including biological and pharmacological actions in immunological,
hepatic, renal, cardiovascular systems as well as an anti-cancer agent. The article also reviews the current efforts to delineate the mechanism of action of Cordycepin in various bio-molecular processes. The study will certainly draw the attention of scientific community to improve the bioactivity and production of Cordycepin for its commercial use in pharmacological and medical fields.