[#2020-04] Coriolus Jedrzejewski, Tomasz...

Chronic inflammation is a well-recognised tumour-enabling component, which includes bioactive molecules from cells infiltrating the tumour microenvironment and increases the risk of cancer progression. Since long-term use of the currently available anti-inflammatory drugs used in cancer therapy causes numerous side effects, the aim of this study was to investigate the effct of an extract isolated from the Coriolus versicolor fungus (CV extract) on HUVEC endothelial cells and MCF-7 breast cancer cells in a pro-inflammatory microenvironment mimicked by...

[#2019-03] Coriolus, Maitake Roca-Lema...

Colorectal cancer (CRC) is one of leading cause of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models. In the present study, we have developed polysaccharide-rich extracts from Trametes versicolor (TV) and Grifola frondosa (GF) fruit bodies. We aim to evaluate the anticancer effects of...

[#2018-07] Blagodatski, Artem et al. Me...

Medicinal mushrooms have been used throughout the history of mankind for treatment of various diseases including cancer. Nowadays they have been intensively studied in order to reveal the chemical nature and mechanisms of action of their biomedical capacity. Targeted treatment of cancer, non-harmful for healthy tissues, has become a desired goal in recent decades and compounds of fungal origin provide a vast reservoir of potential innovative drugs. Here, on example of four mushrooms common for use in Asian and Far Eastern folk medicine we demonstrate the complex and...

[#2015-18] Coriolus Knezevic, Aleksandar...

Trametes species have been used for thousands of years in traditional and conventional medicine for the treatment of various types of diseases. The goal was to evaluate possible antigenotoxic effects of mycelium and basidiocarp extracts of selected Trametes species and to assess dependence on their antioxidant potential. Trametes versicolor, T. hirsuta, and T. gibbosa were the species studied. Antigenotoxic potentials of extracts were assessed on human peripheral white blood cells with basidiocarp and mycelium extracts of the species. The alkaline comet test was used for...

[#2014-15] Coriolus Fang, Xianying et al...

This study reports the combination of Ginkgo flavonoid (GF) and Coriolus versicolor polysaccharide (CVP) in the prevention and treatment of a mouse model of Alzheimer’s disease (AD). GF is a traditional health product, and CVP is the main active ingredient of the medicinal fungus Coriolus versicolor. The Morris water maze test, the Y maze, and the step-through test showed that the combinational use of CVP and GF synergistically improvedmemory in a mousemodel of AD. Based on H&E staining analysis, the combination of CVP and GF decreased the severity of the...

BIORESEARCH UPDATE NEWS LETTER #5 Coriol...

The Activities of Coriolus Ken Babal, C.N.  Coriolus (also known as Trametes) may be the most studied medicinal mushroom of all. The immune-enhancing activities of Coriolus and its constituents have been extensively studied in Japan since the mid-1970s, with over 400 clinical studies conducted on it. It’s common name, turkey tail, is derived from its multicolored, fan-shaped fruiting bodies that grow in overlapping clusters. In traditional Chinese medicine, Coriolus is used to clear dampness and phlegm, heal lung disorders, increase energy, strengthen the physique,...