[#2009-06] Synergistic potentiation of i...

Synergistic potentiation of interferon activity with maitake mushroom D-fraction on bladder cancer cells Brandon Louie, Srinivas Rajamahanty, John Won, Muhammad Choudhury and Sensuke Konno Department of Urology, New York Medical College, Valhalla, NY, USA   To examine whether the combination of interferon (IFN)-α and maitake mushroom D-fraction (PDF), a bioactive mushroom extract, might potentiate the anticancer activity of IFN-α in bladder cancer T24 cells in vitro. IFN-α2B  was able to induce a significant ( ≈ 50%) growth reduction at 20 000 IU/mL, which...

[#2009-05] A phase I/II trial of a polys...

A phase I/II trial of a polysaccharide extract from Maitake mushroom( Grifola frondosa) in breast cancer patients Gary Deng · Hong Lin · Andrew Seidman · Monica Fornier · Gabriella D’Andrea · Kathleen Wesa · Simon Yeung · Susanna Cunningham-Rundles · Andrew J. Vickers · Barrie Cassileth Abstract Background: Cancer patients commonly use dietary supplements to “boost immune function”. A polysaccharide extract from Grifola frondosa (Maitake extract) showed immunomodulatory effects in preclinical studies and there­fore the potential for clinical use. Whether...

[#2008-14] Protein HGFI from the edible ...

Protein HGFI from the edible mushroom Maitake (Grifola frondosa) is a novel 8 kDa class I hydrophobin that forms rodlets in compressed monolayers  Lei Yu,1,2t Baohua Zhang,1 Géza R. Szilvay,2 Ren Sun,1 Janne Jänis,3 Zefang Wang,1 Shuren Feng,1 Haijin Xu,1 Markus B. Linder2 and Mingqiang Qiao1 1College of Life Sciences, Nankai University, 2VTT Biotechnology, Technical Research Centre of Finland 3University of Joensuu, Department of Chemistry Hydrophobins are a group of low-molecular-mass, cysteine-rich proteins that have unusual biophysical properties. They are highly...

[#2008-12] Maitake Obi, Nobuko et al. In...

Inhibitory Effect of TNF-α Produced by Macrophages Stimulated with Grifola frondosa Extract (ME) on the Growth of Influenza A/Aichi/2/68 Virus in MDCK Cells Nobuko Obi,∗,‡ Katsumi Hayashi,§ Tatsurou Miyahara,† Yutaka Shimada,∗,‡Katsutoshi Terasawa,‡,§ Masataka Watanabe,/ Masahide Takeyama, Ryosuke Obi∗ and Hiroshi Ochiai†,‡ ∗Departments of Oriental Medicine and †Human Science, Faculty ofMedicine ‡21st Century COE Program, University of Toyama §Department of Frontier Japanese Oriental (Kampo) Medicine Graduate School of Medicine, Chiba...

[#2008-11] Maitake: Mori, Koichiro et al...

Antiatherosclerotic effect of the edible mushrooms Pleurotus eryngii (Eringi), Grifola frondosa (Maitake), and Hypsizygus marmoreus (Bunashimeji) in apolipoprotein E?deficient mice Mori K(a,b), Kobayashi C(c), Tomita T(c), Inatomi S(b), Ikeda M(c,d) a) Graduate School of Pharmaceutical Sciences, University of Shizuoka, b)Mushroom laboratory, Hokuto Corporation, c)Graduate School of Health Sciences, University of Shizuoka, d)College of Environment and Disaster Research, Fuji Tokoha University In the present study, we examined the antiatherosclerotic effects of 3 edible...

[#2008-10] A Water-Soluble Extract from ...

A Water-Soluble Extract from Grifola frondosa, Maitake Mushroom, Decreases Lipid Droplets in Brown Adipocyte Tissue Cells Katsuhiko MINAMINO, Yumi NAGASAWA and Masaru OHTSURU Department of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women’s University, Nishinomiya 663-8558, Japan (Received August 2, 2007) Summary We investigated the effect of a water-soluble extract from Grifola frondosa, the maitake mushroom, on lipid droplets in brown adipocyte tissue (BAT) cells. This water-solu­ble extract inhibits the conversion of pre white...