[#2008-07] Submerged culture mycelium an...

Submerged culture mycelium and broth of Grifola frondosa improve glycemic responses in diabetic rats. Lo HC, Hsu TH, Chen CY. Department of Medical Education and Research, Changhua Christian Hospital, Changhua, Taiwan. Grifola frondosa ( maitake ), an edible fungus with a large fruiting body and overlapping caps, has been demonstrated to be a natural source of health-promoting substances, mainly due to its polysaccharides β-glucan. By using male Wistar rats injected with saline (normal rats) or nicotinamide plus streptozotocin (diabetic rats), we investigated the effects...

[#2008-06] Grifola frondosa (Maitake Mus...

Grifola frondosa (Maitake Mushroom) Water Extract Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis Through Inhibition of Reactive Oxygen Species and Extracellular Signal-Regulated Kinase Phosphorylation Jong-Suk Lee,1 Byung Chul Park,1 Yu Jin Ko,1 Mi Kyoung Choi,1 Han Gon Choi,1 Chul Soon Yong,1 Jae-Sung Lee,2 and Jung-Ae Kim1 1College of Pharmacy and 2School of Food Technology and Food Service Industry, Yeungnam University, Gyeongsan, Republic of Korea ABSTRACT Grifola frondosa, a large edible mushroom also known as maitake, has been used as a health food...

[#2008-05] Possible immunotherapeutic po...

Possible immunotherapeutic potentiation with D-Fraction in prostate cancer cells Paul Pyo, Brandon Louie, Srinivas Rajamahanty, Muhammad Choudhury and Sensuke Konno* Department of Urology, New York Medical College   Abstract Background: Prostate cancer remains the most common malignancy among elderly men and the second leading cause of cancer death in the United States. Although several conventional therapies are currently available, they have a low efficacy and the more effective treatment modalities need to be established. Interferons (IFNs) are one of such options...

[#2007-11] Maitake Yang, Byung-Keun et a...

Chemical characteristics and immuno-modulating activities of exo-biopolymers produced by Grifola frondosa during submerged fermentation process Byung-Keun Yang, Young-Ah Gu, Yong-Tae Jeong, Hun Jeong, Chi-Hyun Song Abstract The immune-modulating activities and chemical characteristics of exo-biopolymer (EX-GF) produced by a submerged mycelial culture of Maitake (Grifola frondosa) were studied. The EX-GF was fractionated into EX-GF-Fr.1, II, and III by Sephadex G-100 gel chromatography. Anti-complementary activity of EX-GF-Fr. III was highest (71.1%) among them, and its...

[#2007-10] Enhanced insulin-hypoglycemic...

Enhanced insulin-hypoglycemic activity in rats consuming a specific glycoprotein extracted from maitake mushroom Preuss HG, Echard B, Bagchi D, Perricone NV, Zhuang C Department of Physiology, Georgetown University Medical Center Aim: Intraperitoneal glucose tolerance (ipGTT) and insulin challenge (ICT) tests were implemented to evaluate whether a specific glycoprotein extract of maitake mushroom (Grifola frondosa) known as SX-fraction enhances insulin sensitivity in spontaneously hypertensive rats (SHR). Methods: SHR were divided randomly into a control group, a group...

[#2007-09] Stimulating Effects of Grifol...

Stimulating Effects of Grifola frondosa (Maitake) on human osteoblastic cell cultures Saif A, Lindequist U, Wende K Institute of Pharmacy, Ernst-Moritz-Arndt University Greifswald The effect of Grifola frondosa (GF – maitake ) total water extract on two osteoblastic cell cultures (HOS58 and SaOS-2) was investigated to determine if this edible medicinal mushroom has osteoinductive properties. The activity of alkaline phosphate and mineralization were used as indicators for the vitality and maturation of bone cells. The cultivation of human osteosarcoma cells HOS58 for...