[#2004-13] Medicinal Value of Culinary-M...

Medicinal Value of Culinary-Medicinal Maitake Mushroom Grifola frondosa (Dicks.:Fr.) S.F. Gray (Aphyllophoromycetideae). Review. Cun Zhuang and Solomon P Wasser ABSTRACT: Grifola frondosa (Maitake) is a culinary—medicinal mushroom found in some parts of Europe, North America, and Asia. It usually grows naturally on and around the roots of various kinds of deciduous trees. In Japan, it was found in the northern part, and wild G. frondosa was served only at top-class restaurants because of its good flavor, crisp texture, and excellent aroma. Since the mid-1980s, the...

[#2004-12] Usefulness of Anti-Cancer Com...

Usefulness of Anti-Cancer Complementary Immune Therapy with DVM Fraction Shimada, T(a), Shnidman, E(b), Shirota, M(b) a) Department of Veterinary Surgery, Osaka Prefecture University, Japan b) Maitake Products, Inc. D-fraction was used as a complementary therapy for dogs with cancer treated with conventional anti-cancer therapies (surgery and chemotherapy). Due to its appealing taste, the dogs did not offer any resistance to its long-term use. According to pet owners, in almost all cases it helped to maintain or improve the quality of life of the dogs, with no observable...

[#2004-11] Purification and Characteriza...

Purification and Characterization of a Novel Prolyl Aminopeptidase from Maitake (Grifola frondosa) Kazuyuki HIWATASHI,1 Kazuyuki HoRI,I Keitaro TAKAHASHI,’ Akira KAGAYA,2 Shunzo INouE,2 Toshihiro SUGIYAMA,3 and Saori TAKAHASHIl‘t ‘Department of Bioengineering, Akita Research Institute of Food and Brewing,2Akita Jujo Chemicals Co., Ltd.3Department of Biochemistry, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan   We have found a novel prolyl aminopeptidase in Maitake (Grifola frondosa). The enzyme was purified by...

[#2004-10] Effects of a Water-Soluble Bi...

Effects of a Water-Soluble Bioactive Factor from Grifola frondosa, the Mushroom Maitake on Adipocyte Differentiation   Katsuhiko MINAMINO, Yuri YANAGA, Hironori MASUI and Masaru OHTSURUDepartment of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women’s University, A bioactive factor inhibiting adipocyte differentiation was found in the water-soluble fraction of Maitake (Grifola frondosa). The fraction including bioactive factors was isolated by HPLC on Superdex Peptide HR 10/30. This water-soluble fraction was found to inhibit the...

[#2004-09] Maitake beta-glucan MD-fracti...

Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro Lin H, She YH, Cassileth BR, Sirotnak F, Cunningham Rundles S. Integrative Medicine Service, Memorial Sloan-Kettering Cancer Center Previous studies have indicated that MD-fraction (MDF), in which the active component is beta 1,6-glucan with beta 1,3-branches, has anti-tumor activity as an oral agent and acts as an immune adjuvant. Since some other beta glucans appear to promote mobilization of hematopoietic stem cells, the effects of a beta glucan extract from...

[#2004-08] Safety of Maitake D-Fraction ...

Safety of Maitake D-Fraction in Healthy Patients Glauco, S(a), Jano, F(a), Paolo, G(a), Konno, S(b) a) Practicing Physicians in Italy b) New York Medical College Both in vivo and in vitro studies and limited clinical trials thus far support a potent immunostimulatory, anticancer or antitumor as well as apoptosis-inducing activity for D-fraction, which may have great potential for cancer treatment and prevention. However, information on the safety of D-fraction or actual positive or negative effects of D-fraction on healthy human subjects had yet been lacking or...