[#2004-10] Effects of a Water-Soluble Bi...

Effects of a Water-Soluble Bioactive Factor from Grifola frondosa, the Mushroom Maitake on Adipocyte Differentiation   Katsuhiko MINAMINO, Yuri YANAGA, Hironori MASUI and Masaru OHTSURUDepartment of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women’s University, A bioactive factor inhibiting adipocyte differentiation was found in the water-soluble fraction of Maitake (Grifola frondosa). The fraction including bioactive factors was isolated by HPLC on Superdex Peptide HR 10/30. This water-soluble fraction was found to inhibit the...

[#2004-09] Maitake beta-glucan MD-fracti...

Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro Lin H, She YH, Cassileth BR, Sirotnak F, Cunningham Rundles S. Integrative Medicine Service, Memorial Sloan-Kettering Cancer Center Previous studies have indicated that MD-fraction (MDF), in which the active component is beta 1,6-glucan with beta 1,3-branches, has anti-tumor activity as an oral agent and acts as an immune adjuvant. Since some other beta glucans appear to promote mobilization of hematopoietic stem cells, the effects of a beta glucan extract from...

[#2004-08] Safety of Maitake D-Fraction ...

Safety of Maitake D-Fraction in Healthy Patients Glauco, S(a), Jano, F(a), Paolo, G(a), Konno, S(b) a) Practicing Physicians in Italy b) New York Medical College Both in vivo and in vitro studies and limited clinical trials thus far support a potent immunostimulatory, anticancer or antitumor as well as apoptosis-inducing activity for D-fraction, which may have great potential for cancer treatment and prevention. However, information on the safety of D-fraction or actual positive or negative effects of D-fraction on healthy human subjects had yet been lacking or...

[#2004-07] Potential growth inhibitory e...

Potential growth inhibitory effect of maitake D-fraction on canine cancer cells Konno S. Department of Urology, New York Medical College The postulated anticancer effect of D-fraction, the bioactive extract of maitake mushroom, on three types (CF33, CF21, and CL-1) of canine cancer cells was evaluated. The effect of D-fraction on several human cancer cells was also investigated. The effect of other β-glucan products was likewise examined. D-fraction was highly effective on the canine cancer cells, either potently inhibiting cell growth or directly killing cells. Similar...

[#2004-06] Administration of a polysacch...

Administration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice Kodama N, Murata Y, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University We have reported that D-Fraction, a polysaccharide extracted from the edible maitake mushroom (Grifola frondosa), activates immunocompetent cells, thereby eliciting antitumor activity. To extend the application of D-Fraction as a nutritional supplement for healthy people as well as treatment for those with cancer, we investigated the effects of D-Fraction on the immune system in...

[#2003-04] Maitake Talpur, Nadeem et al ...

Effects of niacin-bound chromium, Maitake mushroom fraction SX and (-)-hydroxycitric acid on the metabolic syndrome in aged diabetic Zucker fatty rats Talpur N, Echard BW, Yasmin T, Bagchi D, Preuss HG. Department of Physiology and Biophysics, Georgetown University Medical Center Previous studies in our laboratories have demonstrated that niacin-bound chromium (NBC), Maitake mushroom and (-)-hydroxycitric acid (HCA-SX) can ameliorate hypertension, dyslipidemias and diabetes mellitus, and therefore may be useful in weight management. In the present study, we used aged,...