[#2002-17] Maitake Manohar, V. Effects o...

Effects of a water-soluble extract of maitake mushroom on circulating glucose/insulin concentrations in KK mice Manohar V, Talpur NA, Echard BW, Lieberman S, Preuss HG. Department of Physiology, Georgetown University Medical Center AIM: We examined benefits of a water-soluble extract of maitake mushroom designated as Fraction X (FXM) on the glucose/insulin metabolism of insulin-resistant KK mice, and compared the results of FXM with those of a sulphonylurea, Glipizide. DESIGN: In several acute studies, insulin-resistant KK mice were gavaged with a single dose of varying...

[#2002-11] Cyclooxygenase inhibitory and...

Cyclooxygenase inhibitory and antioxidant compounds from the mycelia of the edible mushroom Maitake ( Grifola frondosa ) Zhang Y, Mills GL, Nair MG. Bioactive Natural Products Laboratory, Department of Horticulture and National Food Safety and Toxicology Center, Biosystems Engineering, Michigan State University The bioassay-guided isolation and purification of the hexane extract of the cultured mycelia of Maitake ( Grifola frondosa ) led to the characterization of a fatty acid fraction and three compounds, ergosterol (1), ergostra-4,6,8(14),22-tetraen-3-one (2), and...

[#2002-10] Molecular cloning and charact...

Molecular cloning and characterization of a cDNA encoding cellobiose dehydrogenase from the wood-rotting fungus Grifola frondosa Makoto Yoshida, Tsuyoshi Ohira, Kiyohiko Igarashi, Hiromichi Nagasawa, Masahiro Samejima GraduateSchoolof Agricultural and Life Sciences, The University of Tokyo   Abstract Cloning of a cDNA encoding cellobiose dehydrogenase (CDH) from the wood-rotting fungus Grifola frondosa, which produces the edible maitake mushroom, was performed using reverse transcription-polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends. The CDH...

[#2002-09] Effects of Maitake mushroom f...

Effects of Maitake mushroom fractions on blood pressure of Zucker fatty rats Talpur N, Echard B, Dadgar A, Aggarwal S, Zhuang C, Bagchi D, Preuss HG. Department of Physiology, Medicine and Pathology, Georgetown University Medical Center A link exists between insulin resistance and many chronic disorders of aging including advancing-age. A safer means to prevent or, at least, slow the erosion of insulin sensitivity would provide a novel approach to better health. We compared the ability of a specific extract labeled fraction SX, as well as whole Maitake powder, fraction ES...

[#2002-08] Antihypertensive and metaboli...

Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains Talpur NA, Echard BW, Fan AY, Jaffari O, Bagchi D, Preuss HG. Department of Physiology and Biophysics, Georgetown University Medical Center Maitake mushroom has been reported to favorably influence hypertension and diabetes mellitus. The purpose of this study was to compare the effects of whole Maitake mushroom powder and two extracts designated as ether soluble (ES) and water soluble (WS) on Zucker fatty rats (ZFR), a model of insulin resistance, and on...

[#2002-07] Can Maitake MD-Fraction Aid C...

Can Maitake MD-Fraction Aid Cancer Patients? Noriko Kodama, PhD, Kiyoshi Komuta, MD, PhD, and Hiroaki Nanba, PhD Abstract Maitake mushroom (Grifola frondosa) MD-fraction containing beta-1,6 glucan with beta-1,3 branched chains has previously exhibited strong anticancer activity by increasing immune-competent cell activity.1,2 In this non­random case series, a combination of MD-fraction and whole maitake powder was investigated to determine its effectiveness for 22- to 57-year-old cancer patients in stages II-IV. Cancer regression or significant symptom improvement was...