[#2003-03] Maitake Kodama, Noriko et al...

Effect of Maitake (Grifola frondosa) D-Fraction on the activation of NK cells in cancer patients Kodama N, Komuta K, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University Maitake D-Fraction, extracted from maitake mushroom, has been reported to exert its antitumor effect in tumor-bearing mice by enhancing the immune system through activation of macrophages, T cells, and natural killer (NK) cells. In a previous study, the combination of immunotherapy with the maitake D-Fraction and chemotherapy suggested that the D-Fraction may have the potential to...

[#2003-02] Relationship between dendriti...

Relationship between dendritic cells and the D-fraction-induced Th-1 dominant response in BALB/c tumor-bearing mice Harada N, Kodama N, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University Dendritic cells (DCs) are known to not only induce the activation of T cells, but are also associated with the differentiation of T cells. The D-fraction, a β-glucan extracted from maitake (Grifola frondosa) which expresses anti-tumor effects by establishing a helper (Th)-1 dominance in BALB/c mice, enhanced IL-12p70 production by DCs, when the ratio of CD8α(+)...

[#2002-18] Maitake Konno, Sensuke Maitak...

Introduction Despite the medicinal aspects of several mushrooms having been passed down through folklore in the Orient, the scientific study of these mushrooms to explore their biological properties has been initiated only within the past 20 years. A number of researchers have particularly focused their attention on one of these mushrooms called maitake {Grifola frondosa) mushroom. ”Maitake” (pronounced “my-tah-keh”) is an edible, tasty mushroom and literally means “dancing mushroom.” Characteristically, it is a giant mushroom that...

[#2002-17] Maitake Manohar, V. Effects o...

Effects of a water-soluble extract of maitake mushroom on circulating glucose/insulin concentrations in KK mice Manohar V, Talpur NA, Echard BW, Lieberman S, Preuss HG. Department of Physiology, Georgetown University Medical Center AIM: We examined benefits of a water-soluble extract of maitake mushroom designated as Fraction X (FXM) on the glucose/insulin metabolism of insulin-resistant KK mice, and compared the results of FXM with those of a sulphonylurea, Glipizide. DESIGN: In several acute studies, insulin-resistant KK mice were gavaged with a single dose of varying...

[#2002-11] Cyclooxygenase inhibitory and...

Cyclooxygenase inhibitory and antioxidant compounds from the mycelia of the edible mushroom Maitake ( Grifola frondosa ) Zhang Y, Mills GL, Nair MG. Bioactive Natural Products Laboratory, Department of Horticulture and National Food Safety and Toxicology Center, Biosystems Engineering, Michigan State University The bioassay-guided isolation and purification of the hexane extract of the cultured mycelia of Maitake ( Grifola frondosa ) led to the characterization of a fatty acid fraction and three compounds, ergosterol (1), ergostra-4,6,8(14),22-tetraen-3-one (2), and...

[#2002-10] Molecular cloning and charact...

Molecular cloning and characterization of a cDNA encoding cellobiose dehydrogenase from the wood-rotting fungus Grifola frondosa Makoto Yoshida, Tsuyoshi Ohira, Kiyohiko Igarashi, Hiromichi Nagasawa, Masahiro Samejima GraduateSchoolof Agricultural and Life Sciences, The University of Tokyo   Abstract Cloning of a cDNA encoding cellobiose dehydrogenase (CDH) from the wood-rotting fungus Grifola frondosa, which produces the edible maitake mushroom, was performed using reverse transcription-polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends. The CDH...