[#2002-03] A polysaccharide, extract fro...

A polysaccharide, extract from Grifola frondosa, induces Th-1 dominant responses in carcinoma-bearing BALB/c mice Kodama N, Harada N, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University A polysaccharide, designated as the D-fraction, extracted from maitake (Grifola frondosa), was reported to have anti-tumor effects by activating macrophages and T cells in C3H/HeN mice in which a Th-1 dominant response was established. In this study using BALB/c mice in which a Th-2 response is genetically dominant, D-fraction reduced the expression of Th-2 cytokine...

[#2001-12] Cholesterol-lowering effects ...

Cholesterol-lowering effects of maitake (Grifola frondosa) fiber, shiitake (Lentinus edodes) fiber, and enokitake (Flammulina velutipes) fiber in rats Fukushima M, Ohashi T, Fujiwara Y, Sonoyama K, Nakano M. Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine The effects of mushroom fibers on serum cholesterol and hepatic low-density lipoprotein (LDL) receptor mRNA in rats were investigated. Rats were fed a cholesterol-free diet with 50 g/kg cellulose powder (CP), 50 g/kg maitake (Grifola frondosa) fiber (MAF), 50 g/kg shiitake...

[#2001-11] Maitake (Grifola frondosa) im...

Maitake (Grifola frondosa) improve glucose tolerance of experimental diabetic rats Horio H, Ohtsuru M. Department of Food Science and Nutrition, Faculty of Home Economics, Nishikyushu University We have previously reported that rats with diabetes induced by injecting streptozotocin into neonates showed remarkably lower blood glucose, urine volume, and glucosuria after administration of Maitake (Grifola frondosa). In the present study, we investigated the effects of Maitake on insulin concentration, organ weight, serum composition, and islets of Langerhans in...

[#2001-10] Nitric oxide-mediated antitum...

Nitric oxide-mediated antitumor activity induced by the extract from Grifola frondosa (Maitake mushroom) in a macrophage cell line, RAW264.7 Sanzen I, Imanishi N, Takamatsu N, Konosu S, Mantani N, Terasawa K, Tazawa K, Odaira Y, Watanabe M, Takeyama M, Ochiai H. Dept. of Clinical Nursing, Faculty of Medicine, Toyama Medical and Pharmaceutical University We have investigated D-fraction (MDF) extracted from Grifola frondosa ( Maitake mushroom) on the inducible nitric oxide synthase (iNOS)-mediated nitric oxide (NO) production in RAW264.7 (RAW) cells, a murine...

[#2001-09] A Possible Hypoglycemic Effec...

A Possible Hypoglycemic Effect of Maitake Mushroom on Type 2 Diabetes Patients Konno S, Tortorelis G, Fullerton SA, Samadi AA, Hettiarachchi J, Tazaki H Department of Urology, New York Medical College Two patients diagnosed with Type 2 diabetes had significantly elevated fasting blood glucose (FBG) levels even with administration of glibenclamide, a commonly-prescribed diabetes drug. Both patients were given Maitake mushroom caplets (500 mg) in daily doses, along with their glibenclamide, and experienced a sharp drop in blood glucose levels to within the normal range....

[#2001-08] Maitake SX-Fraction: Possible...

Maitake SX-Fraction: Possible Hypoglycemic Effect on Diabetes Mellitus Sensuke Konno, Ph.D. Diabetes mellitus is a metabolic dis­order characterized by persistent hyperglycemia affecting more than 16 million people in the United States and some 250 million people worldwide.1 The prevalence of diabetes is increasing by 4–5 percent every year with an estimated 40–45 percent of people over 65 years old at risk.2 To enhance peripheral insulin sensitivi­ty, pharmaceuticals, such as troglitazone8 and metformin,9,10 have been used. Although improved glycemic control with...