[#1995-02] Inactivation of (1-3)-β-D-Glu...

Inactivation of (1-3)-β-D-Glucan in Mice Toshihide MIURA, Naohito OHNO, Masahiro SUDA, Noriko N. MIURA, Shigehiko SHIMADA, and Toshiro YADOMAE Tokyo University of Pharmacy and Life Science (formerly Tokyo College of Pharmacy), Tokyo Japan and Kitasato University Hospital, Department of Pharmacy, Kanagawa, Japan. Intraperitoneally or intravenously administered (1–>3)-β-D-glucan remained in the liver and spleen, for a long time without major structural changes, but the priming activity to lipopolysaccharide (LPS)-triggered tumor necrosis factor-α (TNF-α)...

[#1995-01] Activity of Maitake D-Fractio...

Activity of Maitake D-Fraction to Inhibit Carcinogenesis and Metastasis Nanba, H Department of Microbial Chemistry, Kobe Pharmaceutical University Of all the medicinal mushrooms studied by the author, the Maitake mushroom (Grifola frondosa) has the strongest antitumor activity in tumor growth inhibition both when administered orally and intraperitoneally. In fact, most of the other mushroom extracts are reported ineffective when given orally. In this report, the author investigated Maitake’s activities on the inhibition of carcinogenesis and metastasis in mouse...

[#1994-11] Chemical Modification and Ant...

Chemical Modification and Antitumor Activity of Polysaccharides from the Mycelium of Liquid-Cultured Grifola frondosa Zhuang, C(a), Mizuno, T(b), Ito, H(c), Shimura, K(c) a) The United Graduate School of Agricultural Sciences, Gifu University, b) Faculty of Agriculture, Shizuoka University, c) School of Medicine, Mie University Twenty-three chemically modified polysaccharides, including five polyaldehyde-, ten polyalcohol-, four formylated-polysaccharides and four formolysis products of polysaccharides, were prepared from nine mycelial polysaccharides of Grifola frondosa (...

[#1994-10] Antitumor Activity and Immuno...

Antitumor Activity and Immunological Property of Polysaccharides from the Mycelium of Liquid-Cultured Grifola frondosa Zhuang, C(a), Mizuno, T(b), Ito, H(c), Shimura, K(c), Sumiya, T(d), Kawade, M(d) a) The United Graduate School of Agricultural Sciences, Gifu University, b) Faculty of Agriculture, Shizuoka University, c) School of Medicine, Mie University, d) Iwade Mushroom Institute, Japan A systematic method for the fractionation and purification of antitumor polysaccharide fractions from the mycelium of liquid-cultured Grifola frondosa ( maitake ) was established....

[#1994-09] Fractionation and Antitumor A...

Fractionation and Antitumor Activity of Polysaccharides from Grifola frondosa Mycelium Zhuang, C, Mizuno, T, Ito, H, Shimura, K, Sumiya, T, Kawade, M The United Graduate School of Agricultural Sciences, Gifu University We developed a method for the fractionation and purification of antitumor polysaccharides, considered to be a type of immunopotentiator or BRM (biological response modifier), from the mycelium of liquid cultured Grifola frondosa ( maitake ). The active polysaccharide fractions that showed higher antitumor activity were considered to be heteroglycans or their...

[#1994-07] Maitake: Shimaoka, Iwao et al...

EFFECTS OF A COPPER-BINDING PEPTIDE FROM THE MUSHROOM GRIFOLA FRONDOSA ON INTESTINAL COPPER ABSORPTION Iwao Shimaoka, M.S.1*, Sachiko Ishiyama, B.S.2, Kohsuke Nishino, Ph.D.2, Yoshinori Itokawa, Ph.D.’ ‘Department of Environmental Medicine. Graduate Schoolof Medicine. KyotoUniversity, Kyoto, Japan2Department of Home Economics, Dohshisha Women’s College,Kyoto, Japan ABSTRACT The effect of a copper-binding peptide, purified previously from the fruit bodies of the mushroom, Grifola frondosa ( maitake ) , on copper absorption was investigated by using portal...