[#2010-12] Maitake beta-glucan promotes ...

Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity Hong Lin • Elisa de Stanchina • Xi Kathy Zhou • Feng Hong • Andrew Seidman • Monica Fornier • Wei-Lie Xiao • Edward J. Kennelly • Kathleen Wesa • Barrie R. Cassileth • Susanna Cunningham-Rundles Maitake Abstract Bone marrow myelotoxicity is a major limita­tion of chemotherapy. While granulocyte colony stimulat­ing factor (G-CSF) treatment is effective, alternative approaches to support hematopoietic recovery are sought. We...

[#2010-11] A polysaccharide extracted fr...

A polysaccharide extracted from Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine colon cancer   Yuki Masuda • Koichi Ito • Morichika Konishi • Hiroaki Nanba   Abstract We previously isolated the novel heteropoly­saccharide maitake Z-fraction (MZF) from the maitake mushroom (Grifola frondosa), and demonstrated that MZF significantly inhibited tumor growth by inducing cell-mediated immunity. In this study, we demonstrated that MZF upregulated the expression of CD80, CD86, CD83, and...

[#2010-10] Commonly consumed and special...

Commonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells Keith R Martin and Sara K Brophy Nutrition Program, Healthy Lifestyles Research Center, Arizona State University,  USA Abstract Worldwide, over one million women will be newly diagnosed with breast cancer in the next year. Moreover, breast cancer is the second leading cause of cancer death in the USA. An accumulating body of evidence suggests that consumption of dietary mushrooms can protect against breast cancer. In this study, we tested and compared the...

[#2010-09] Both common and specialty mus...

Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment Keith R Martin Abstract Background: Cardiovascular disease (CVD) is a leading cause of mortality in the United States as well as globally. Epidemiological studies show that regular fruit and vegetable consumption reduces CVD risk, in part, due to antioxidant activity and immunomodulation since oxidative stress and inflammation are features of atherogenesis. Accumulating evidence also shows that...

[#2010-08] Inorganic Iodine Content of c...

INORGANIC IODINE CONTENT OF COMMON, EDIBLE MUSHROOMS J. VETTER* Department of Botany, Faculty of Veterinary Science, Szent István University, Hungary The edible mushrooms have different valuable chemical properties (proteins, minerals, aromatic compounds, low lipid and energy contents, etc.) but there are practically no data about the iodine content. The aim of this work was to produce new data on the iodine content of the common edible mushrooms. The inorganic iodine contents of different wild growing (n=49) and cultivated (n=30) mushroom samples were analysed. A partly...

[#2010-07] Grifola frondosa ( Maitake ) ...

Grifola frondosa ( Maitake ) water extract alleviates intestinal inflammation by suppressing TNF-α production and its signaling Jong Suk Lee1*, Su-Young Park1*, Dinesh Thapa1, Mi Kyoung Choi1, Ill-Min Chung2, Young-Joon Park3, Chul Soon Yong1, Han Gon Choi1 and Jung-Ae Kim1 1College of Pharmacy Yeungnam University, Korea 2College of Life and Environmental Sciences Konkuk University Seoul, Korea 3Research Center Samil Pharmaceutical Co. Ltd. Korea Abstract   TNF-α is a major cytokine involved in inflammatory bowel disease (IBD). In this study, water extract of Grifola...