[#2010-06] Potential Antitumor Activity ...

Potential Antitumor Activity of a Low-Molecular-Weight Protein Fraction from Grifola frondosa Through Enhancement of Cytokine Production Noriko Kodama,1,2 Shigeto Mizuno,3 Hiroaki Nanba,4 and Naoaki Saito1 1Laboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University; and Departments of 2Basic Educational Center for Pharmacy and 3Medical Pharmaceutics, 4Kobe Pharmaceutical University, Kobe, Japan ABSTRACT Edible mushrooms contain an abundance of immune-enhancing nutritients. Some of these compounds, referred to as biological response modifiers (BRMs),...

[#2010-05] Anti-fungal Cell Wall β-gluca...

Anti-fungal Cell Wall β-glucan Antibody in Animal Sera Ken-ichi Ishibashi, Chikaku Dogasaki, Masuro  Motoi, Noriko Miura,Yoshiyuki Adachi, Naohito Ohno β-Glucan is a major component of the cell walls and pathogen-associated microbial patterns of fungi. We previously reported the presence of an antibody which reacts to β-glucan, anti-β-glucan (BG) antibody, in human sera. In livestock and domestic pets, the antibody’s response to fungal cell wall β-glucan is little understood. In this study, we examined the existence and reactivity of anti-BG antibody in...

[#2010-04] Maitake Mushroom (Grifola fro...

Maitake Mushroom (Grifola frondosa) Extract Induces Ovulation in Patients with Polycystic Ovary Syndrome: A Possible Monotherapy and a Combination Therapy After Failure with First-Line Clomiphene Citrate Jui-Tung Chen, MD, PhD, Kunihiko Tominaga, MD, DrPh, PhD, Yoshiaki Sato, MD, PhD,3Hideo Anzai, BS, BS, RPh, and Ryo Matsuoka, MD, PhD Abstract Background: Insulin resistance is a prominent feature of polycystic ovary syndrome (PCOS), and insulin-sen­sitizing drugs are used to induce ovulation. Recently, it was reported that an extract from Maitake mushroom (Grifola...

[#2009-15] The effects of whole mushroom...

The effects of whole mushrooms during inflammation Sanhong Yu1, Veronika Weaver1, Keith Martin2 and Margherita T Cantorna*1 1Center for Immunology and Infectious Disease, Department of Veterinary and Biomedical Science, The Pennsylvania State University, USA and 2Department of Nutrition, Arizona State University, USA   Abstract Background: Consumption of edible mushrooms has been suggested to improve health. A number of isolated mushroom constituents have been shown to modulate immunity. Five commonly consumed edible mushrooms were tested to determine whether whole...

[#2009-14] Maitake Mushroom (Grifola fro...

Maitake Mushroom (Grifola frondosa): Systematic Review by the Natural Standard Research Collaboration Catherine Ulbricht, PharmD, Wendy Weissner, BA, Ethan Basch, MD, Nicole Giese, MS, Paul Hammerness, MD, Erica Rusie–Seamon, PharmD, Minney Varghese, BS, Jen Woods, BS The objective of this study was to evaluate the scientific evidence on maitake, including expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing. This review serves as a clinical support tool. Electronic searches were conducted in...

[#2009-13] Antitumor effects of a water-...

Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines KOHEI SHOMORI1, MAKO YAMAMOTO1, ICHIRO ARIFUKU2, KAZUKI TERAMACHI1 and HISAO ITO1 1Division of Organ Pathology, Department of Microbiology and Pathology, Faculty of Medicine,Tottori University, Japan 2Industrial Research Institute of Tottori Prefecture, Sakaiminato, Japan Abstract. We investigated the effects of a water-soluble extract of Maitake (Grifola frondosa), a Japanese edible mushroom, on the proliferation and cell death of four human gastric cancer...