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Ganoderma lucidum (G. lucidum), a traditional Chinese medicine, has been used for the treatment of various
diseases including cancer and atherosclerosis. In this study, the positive effect of G. lucidum on metabolic
syndrome was investigated in more detail by the use of 3T3-L1 pre-adipocyte cells. Treatment of 3T3-L1 cells
with G. lucidum extract (GE) significantly promoted adipocyte differentiation and adiponectin production in a
dose-dependent manner, as assessed by Oil-Red O staining, quantitative RT-PCR and ELISA. Treatment with
GW9662, an inhibitor for peroxisome...