[#2004-14] Effects of Ganoderma lucidum ...

Effects of Ganoderma lucidum on Apoptotic and Anti-inflammatory Function in HT-29 Human Colonic Carcinoma Cells Kee-jong Hong, Dale M. Dunn, Chwan-Li Shen, Barbara C. Pence* Department of Pathology,TexasTechUniversityHealthSciencesCenter Ling Zhi extract (LZE) is a herbal mushroom preparation which been used world wide for the prevention and treatment of various cancers. The current study was designed to evaluate these claims in human colon cancer cells in terms of cancer preventive mechanisms. Results have demonstrated induction of apoptosis, anti-inflammatory action and...

[#2003-05] Hepatoprotective Activity and...

Hepatoprotective Activity and the Mechanisms of Action of Ganoderma lucidum (Curt.:Fr.) 0. Karst. (Ling Zhi, Reishi Mushroom) (Aphyllophoromycetideae) (Review) Yihuai Gao,’ Zhi-Bin Lin,2 Min Huang,3 and Shufeng Zhou4,* ‘Institute of Food, Nutrition and Human Health, Massey University, Auckland, NZ; 2Department of Pharmacology, Health Science Center, Peking University, Beijing 100083, China; 3Department of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, The People’s Republic of China; 4Department of Pharmacy,...

[#2002-20] Reishi Lin, Shwu-Bin et al Tr...

The medicinal mushroom Ganoderma lucidum (G. lucidum) has been used in the Orient for the prevention and treatment of various diseases including cancer. Except for the immune enhancing properties of its polysaccharide constituent, very little is known about the anticancer activity of another major constituent, triterpenes. In this report, we studied the anticancer mechanism of triterpene-enriched extracts from G. lucidum. The triterpeneenriched fraction, WEES-G6, was prepared from mycelia of G. lucidum by sequential hot water extraction, removal of ethanol-insoluble...

[#2002-15] Reishi Zhou, Shufeng et al Th...

The Immunomodulating Eifects of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Ling Zhi, Reishi Mushroom) (Aphyllophoromycetideae) Shufeng Zhou and Yihuai Gao ABSTRACT: This review highlights the recent research progress in the study of immunomodulating effects of Ganoderma lucidum (Curt.: Fr.) P. Karst. (reishi mushroom), which belongs to the higher Basidiomycetes. Several major substances with potent immunomodulating action have been isolated. These include polysaccharides (in particular β-D-glucans), proteins, and triterpenoids. The major immunomodulating effects of these...

[#2002-14] Effects of Total Triterpenoid...

Effects of Total Triterpenoids Extract from Ganoderma lucidum (Curt.: Fr.) P. Karst. (Reishi Mushroom) on Experimental Liver Injury Models Induced by Carbon Tetrachloride or D-Galactosamine in Mice Ming-Yu Wang,’ Qiang Liu,’ Qing-Ming Che,2 and Zhi-Bin Lin’ ‘Department of Pharmacology, School of Basic Medical Sciences; and 2Department of Traditional Chinese Medicine Drugs, College of Pharmacy, People’s Republic of China   ABSTRACT: The effect of total triterpenoids extract isolated from Reishi, Ganoderma lucidum (Curt.: Fr.) P. Karst....

[#2002-13] A Phase I/II Study of a Ganod...

A Phase I/II Study of a Ganoderma lucidum (Curt .: Fr.) P. Karst. (Ling Zhi, Reishi Mushroom) Extract in Patients with Chronic Hepatitis B Yihuai Gao,’ Shufeng Zhou,2,* Guoliang Chen,3 Xihu Dai,4 Jingxian Ye,5 and He Gao’ 1 New Zealand Institute of Natural Medicines, Auckland, New Zealand; 2 Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore  3Shanghai Academy of Agricultural Sciences, Shanghai, China; 4Fuzhou General Hospital of Nanjing Military Region of the Peoples’ Liberation Army, Fuzhou, Fujian, China; and...