[#1997-05] Sterol Constituents from the Fruit Bodies of Grifola frondosa, T. Ishizuka et al.

Sterol Constituents from the Fruit Bodies of Grifola frondosa

Ishizuka, T, Yaoita, Y, Kikuchi, M

Tohoku College of Pharmacy

Four new sterols, 5α, 6α-epoxy-(22E, 24R)-ergosta-8 (14), 22-diene-3β, 7β-diol (1), (22E, 24R)-ergosta – 8,22-diene-3β,5α,6β,7α-tetrol (2), (22E,24R)-ergosta-7,9(11), 22-triene-3β,5α,6β-triol (3) and 3β,5α,6β-trihydroxy-(22E,24R)-ergost-22-en-7-one (4), have been isolated from the fruit bodies of Grifola frondosa ( maitake ) together with fourteen known ones (5-18), of which two (5 and 6) are reported for the first time from a natural source.  The structures of these compounds were elucidated on the basis of structural data.