REFERENCES
[#2013-23] Lion’s Mane Wong, Jing Yang et al. Gastroprotective effect of Lion’s Mane
Hericium erinaceus is a famous tonic in oriental medicine. The gastroprotective effects of aqueous extract of H. erinaceus against ethanol-induced ulcers in Sprague Dawley rats were investigated. The possible involvements of lipid peroxidation, superoxide dismutase, and catalase were also investigated. Acute toxicity study was performed.The effects of aqueous extract of H. erinaceus on the ulcer areas, ulcer inhibition, gastric wall mucus, gross and histological gastric lesions, antioxidant levels, and malondialdehyde (MDA) contents were...
read more[#2013-22] Cordyceps Lo, Hui-Chen et al. A Systematic Review of the Mysterious Caterpillar Fungus
The caterpillar fungus Ophiocordyceps sinensis (syn. Cordyceps sinensis), which was originally used in traditional Tibetan and Chinese medicine, is called either “yartsa gunbu” or “DongChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo)” (“winter wormsummer grass”), respectively. The extremely high price of DongChongXiaCao, approximately USD $20,000 to 40,000 per kg, has led to it being regarded as “soft gold” in China. The multi-fungi hypothesis has been proposed for DongChongXiaCao; however, Hirsutella sinensis is the...
read more[#2013-21] Cordyceps Mg, Shashidhar et al. Bioactive principles from Cordyceps sinensis, A potent food supplement
Cordyceps sinensis (CS) is a well-known entamophagus fungus, naturally distributed in the Tibetan Plateau of Asia and Himalayas. Recently this synonym is transferred to Ophiocordyceps by both scientific and non-scientific communities. It is widely used as a tonic and medicinal food in traditional Chinese medicine (TCM), as it possess wonderful health benefits. To support its functional attributes, various investigations have been carried out to find out its adaptogenic, aphrodisiac, anti-oxidant, anti-aging, neuroprotective,...
read more[#2013-20] Cordyceps Tuli, Hardeep et al. Phamacological and therapeutic potential of Cordyceps
Abstract An entomopathogenic fungus, Cordyceps sp. has been known to have numerous pharmacological and therapeutic implications, especially, in terms of human health making it a suitable candidate for ethno-pharmacological use. Main constituent of the extract derived from this fungus comprises a novel bio-metabolite called as Cordycepin (30deoxyadenosine) which has a very potent anti-cancer, antioxidant and anti-inflammatory activities. The current review discusses about the broad spectrum potential of Cordycepin including biological...
read more[#2013-19] Cordyceps Meena, Harsahay et al. Sub-acute toxicity of cultured mycelia, Himalayan entomogenous fungus Cordyceps
Oral administration of laboratory cultured mycelia powder of C. sinensis did not show any sign of toxicity as no significant change was observed in organ weight and serological parameters in rats. However, there was a significant increase in food intake, body weight gain and hematological parameters like WBC, RBC, Hb and lymphocytes in treated groups. Histopathology of vital organs also supported the non toxic effect of C. sinensis. The results conclude that laboratory cultured mycelia powder of C. sinensis is safe and non toxic up to 2 g/kg...
read more[#2013-18] Meshima Kang, Chan Moo et al. Anticancer effect of phellinus linteus potential clinical application in treating pancreatic ductal adenocarcinoma
Pancreatic cancer (ductal adenocarcinoma) is one of the most lethal malignancies in gastrointestinal system. Till now, only margin-negative pancreatectomy is known to be the best treatment option for long-term survival. However, the resection rate is reported to be less than 20%. Even in cases of curative resection, most patients generally experience disease recurrence and ultimately die of metastatic disease. Therefore, surgery alone is not enough and adjuvant systemic chemotherapy should be considered for proper management of pancreatic...
read more[#2013-17] Reishi Wu, Xin et al. Hepatoprotective Effects of Aqueous Extract from Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum on alpha Amanitin-Induced Liver Injury in Mice
ABSTRACT: The Lingzhi or Reishi mushroom Ganoderma lucidum is a well-known traditional medicinal mushroom that has been shown to have obvious hepatoprotective effects. The aim of this study was to evaluate the hepatoprotective effects of G. lucidum aqueous extracts (GLEs) on liver injury induced by α-amanitin (α-AMA) in mice and to analyze the possible hepatoprotective mechanisms related to radical scavenging activity. Mice were treated with α-AMA prepared from Amanita exitialis and then administrated with GLE after the α-AMA injection....
read more[#2013-16] Poria Cheng, Shujie et al. Triterpenes from Poria cocos suppress growth and invasiveness of pancreatic cancer cells through the downregulation of MMP-7
Abstract. Poria cocos is a medicinal mushroom that is widely used in traditional Asian medicine. Here, we show that a characterized mixture of triterpenes extracted from P. cocos (PTE) and three purified triterpenes: pachymic acid (PA), dehydropachymic acid (DPA) and polyporenic acid C (PPAC) suppress the proliferation of the human pancreatic cancer cell lines Panc-1, MiaPaca-2, AsPc-1 and BxPc-3. Moreover, the most effective compound, PA, only slightly affects the proliferation of HPDE-6 normal pancreatic duct epithelial cells. The...
read more[#2013-15] Lion’s Mane Khan, Asaduzzaman et al. Hericium erinaceus: an edible mushroom with medicinal values
Mushrooms are considered as nutritionally functional foods and source of physiologically beneficial medicines. Hericium erinaceus, also known as Lion’s Mane Mushroom or Hedgehog Mushroom, is an edible fungus, which has a long history of usage in traditional Chinese medicine. This mushroom is rich in some physiologically important components, especially β-glucan polysaccharides, which are responsible for anti-cancer, immuno-modulating, hypolipidemic, antioxidant and neuro-protective activities of this mushroom. H. erinaceus has also been...
read more[#2013-14] Reishi Aguirre-Moreno, Alma et al. Anticonvulsant and Neuroprotective Effects of Oligosaccharides from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes)
An oligosaccharide fraction isolated from the mycelium of the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (GLOS) was separated by size-exclusion chromatography. The chemical structure of GLOS consists of a disaccharide repeating unit [-4-b-1-Galf(1-6)-O-(β-Glcp)−1-]n (n=3,4). In addition, this study was undertaken to determine the possible anticonvulsant and neuroprotective effects of GLOS (10–80 mg/kg) on kainic acid (KA)-induced seizures. The behavioral alterations and histopathology of hippocampal neurons were studied. Our...
read more