The present study suggests that SXF may specifically target the insulin signal pathway, and, in particular, the IR and IRS-1 therein that trigger the subsequent signaling events. As a result, SXF could activate such an impaired signal pathway through high Glc or under a hyperglycemic milieu, thereby ultimately facilitating Glc uptake. This may then account for possible hypoglycemic action of SXF.
read moreAlthough several conventional therapeutic options for advanced renal cell carcinoma (RCC) are currently available, the unsatisfactory outcomes demand establishing more effective interventions. D-fraction (PDF), a bioactive proteoglucan of Maitake mushroom, demonstrates anticancer and immunomodulatory activities, which are also shown to be potentiated by vitamin C (VC).We thus hypothesized that a combination of PDF and VC (PDF + VC) could be an alternative approach to more effectively inhibit the growth of RCC. Study design. We examined the...
read moreMaitake Mushroom (Grifola frondosa) Maitake is an edible and medicinal mushroom grows in the northern part of the Temperate Zone in the Northern Hemisphere found in Japan, China, Europe and North America. Wild Maitake can be harvested in September and October. It forms large hands, mainly near the roots of big fagaceous trees such as white oak, beech, and tanbark oak. It grows in persimmon, plum, apricot, Prunus ume and oak trees. It invades the core of these trees. It decomposes lignin and leaves the cellulose, which is the cause of so-called...
read moreLion’s Mane Mushroom (Hericium erinaceus) The brain tonic, Go beyond ginkgo. Lion’s Mane (Hericium erinaceus) is a mushroom with long cascading tendrils, hence the name. It is also known as “bear’s head,” “monkey’s head,” “hedgehog fungus,” and “Hou Tou Gu” in Chinese. Recent studies support its traditional use for promoting healthy digestive and immune system functions. However, more promising is its ability to stimulate synthesis of the Nerve Growth Factor (NGF), which...
read moreCordyceps Mushroom (Cordyceps sinensis) Stamina, Endurance and Sex Drive Cordyceps (Cordyceps sinensis) is a special mushroom that can only be found in the mountains more than 12,000 feet above sea level in the southwestern areas of China and Nepal. Cordyceps is regarded as one of the most valuable and expensive herbs in traditional Chinese medicine. They say that, in ancient China, Cordyceps was taken as an elixir of life and only the imperial family could afford it. In 1993, women track athletes from China astonished the world as they broke...
read moreCordyceps is a fastidious pathogenic fungus infecting insects, and recent years have witnessed rapid progress in its medical properties. In this study, a wild isolate, C. cicadae MP12, was characterized through in vitro cultivation and its nuclear small-subunit (SSU) ribosomal DNA (rDNA) data. In vitro culture of C. cicadae MP12 was established by growing its fruiting bodies in a solid matrix. C. cicadae MP12 was inoculated into Cryptotympana atrata cicada pupae for in vivo culture, where the fungi developed its fruiting body as well. The...
read moreAbstract. – Background and Objectives: Diabetes mellitus inducing a leading cause of morbidity are widespread in the entire globe. The present study was to investigate the antidiabetic potency and mechanism of a proteoglycan extract, named FYGL (Fudan-Yueyang-G. lucidum), from the fruiting bodies of Ganoderma Lucidum as published recently, using streptozotocin- induced type 2 diabetic mellitus (T2DM) rats. Material and Methods: The T2DM model rats were treated with FYGL as well as metformin and rosiglitazone. The levels of plasma...
read moreReishi Mushrooms (Ganoderma lucidum) Elixir of Immortality. Reishi Mushroom (Ganoderma lucidum), also known as “Ling Zhi” in China, “Mannen-take” in Japan and “Young Zhi” in Korea, is one of the most famous medicinal mushrooms in the world. Reishi has been prized as the “Mushroom of Immortality” for thousands of years. During the last two decades, researchers have found various bioactive constituents in Reishi which have a wide range of actions, including boosting immune function; anti-viral and...
read moreWe present a model case study of the activity of aqueous extract of Hericium erinaceus fresh fruit bodies in promoting functional recovery following crush injury to the peroneal nerve in adult female Sprague-Dawley rats. The aim was to explore the possible use of this mushroom in nerve repair. The activities of aqueous extract were compared to activities exhibited by mecobalamin (vitamin B12), which has been widely used in the treatment of peripheral nerve disorders. Analysis of walking track indicated that return of hind limb function and...
read moreTremella Mushrooms (Tremella fuciformis) Women’s aid for beauty from the Inside, Out. Tremella Mushroom (Tremella fuciformis), also called Silver Ear Mushroom with its large loose lobes, has been used in Asia as a Qi and immune tonic. Tremella has been also highly prized as a youthful skin tonic for a healthy complexion. It is said that imperial Concubine Yang (719-756), considered to be one of the most beautiful women in Chinese history, used Tremella for her facial and body maintenance. As such, Chinese women have been taking Tremella...
read more