Immune enhancing effects of WB365, a novel combination of Ashwagandha (Withania somnifera) and Maitake (Grifola frondosa) extracts Vaclav Vetvicka and Jana. Vetvickova. Dapartment of Pathology, University of Louisville, Louisville, KY USA Abstract Background: Stress has been found to significantly reduce the abilities of the immune system to fight infection!. One of the ways to overcome the defect of the immune system is the strengthening of the defense reactions by nutrition. Aims: To evaluate immune enhancing effects of the following...
read moreABSTRACT This study aimed to determine the effects of an extract from Maitake mushroom (“SX-fraction”, SX) on ovulation in patients with polycystic ovary syndrome (PCOS). Thirty patients were randomly assigned to either of the following two treatment arms for three months: the SX group (n = 15), which prescribed 207 mg/day of SX, and the control group (n = 15), which received 7.5 g/day of Shakuyaku-Kanzo-To (SKT; a Chinese herbal medicine). Ovulation was judged by the change of basal body temperature and ultrasonography. During the...
read moreMaitake (D Fraction) Mushroom Extract Induces Apoptosis in Breast Cancer Cells by BAK-1 Gene Activation Raquel Soares, Manuela Meireles,1 Ana Rocha,1 Ana Pirraco,1 Diego Obiol,2 Eliana Alonso,2 Gisela Joos,2 and Gabriela Balogh 1Department of Biochemistry, Faculty of Medicine, University of Porto Foundation, Porto, Portugal. 2Center for Scientific and Technical Investigation, Cerzos-Conicet, Bahı´a Blanca, Argentina. ABSTRACT For many years mushrooms have been used empirically in traditional medicine to treat several diseases. Study...
read moreSoluble β-glucan from Grifola frondosa induces proliferation and Dectin-1/Syk signaling in resident macrophages via the GM-CSF autocrine pathway Yuki Masuda,*,1 Takuya Togo,* Shigeto Mizuno,† Morichika Konishi,* and Hiroaki Nanba* Departments of *Microbial Chemistry and †Medical Pharmaceutics, Kobe Pharmaceutical University, Kobe, Japan ABSTRACT MD-Fraction, a highly purified, soluble β-(1,3) (1,6)-glucan obtained from Grifola frondosa (an oriental edible maitake mushroom), has been reported to inhibit tumor growth by modulating host...
read moreNonvolatile Taste Components of Culinary-Medicinal Maitake Mushroom, Grifola frondosa (Dicks.:Fr.) S.F. Gray Shih-Jeng Huang,1 Shu-Yao Tsai,2 Shin-Yi Lin,3 Chih-Hung Liang,1 & Jeng-Leun Mau3,* 1Department of Nutrition and Health Science, Chungchou Institute of Technology, Yuanlin, Changhua 51003, Taiwan, R.O.C.; 2Department of Health and Nutrition Biotechnology, Asia University, 500 Liufeng Road, Wufeng, Taichung 41354, Taiwan, R.O.C; 3Department of Food Science and Biotechnology, National Chung-Hsing University, 250 Kuokuang Road,...
read moreMaitake (Grifola frondosa) Abstract and key points Written by Markus Horneber and the CAM-Cancer Consortium. Maitake is a mushroom indigenous to many Asian countries. Commercial preparations are available as preserved whole fruiting bodies, pulverized fruiting bodies and extracts from the mycelium. Like other species from this phylum, Maitake contains polysaccharides (alpha-/beta-homo- and heteroglycans), proteins, nucleic and amino acids, minerals and trace elements, ergosterin, several vitamins and provitamins, phenols and flavonoids. The...
read moreEffects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice Koichiro MORI 2I, Yutaro OBARA2, Takahiro MORIYAI, Satoshi INATOMI2, and Norimichi NAKAHATA’ IDepartment of Cellular Signaling, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai 980-8578 and 2Mushroom Laboratory, 1-lokuto Corporation, 800-8 Shimokomazawa., Nagano 381-0008, Japan ABSTRACT The mushroom Hericium erinaceus ( Lion’s Mane ) has been used as a food and herbal medicine...
read moreObjective: The objective of this study was to examine the effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy elderly subjects. Design: Twenty (20) healthy elderly (age 50–75 years) subjects were enrolled in this double-blind, placebocontrolled, prospective trial. The subjects were taking either Cs-4 333mg or placebo capsules 3 times a day for 12 weeks. Measurement: Subjects received baseline screening including physical examination and laboratory tests. Maximal incremental exercise testing was performed on a...
read moreGanoderma lucidum (G. lucidum), a traditional Chinese medicine, has been used for the treatment of various diseases including cancer and atherosclerosis. In this study, the positive effect of G. lucidum on metabolic syndrome was investigated in more detail by the use of 3T3-L1 pre-adipocyte cells. Treatment of 3T3-L1 cells with G. lucidum extract (GE) significantly promoted adipocyte differentiation and adiponectin production in a dose-dependent manner, as assessed by Oil-Red O staining, quantitative RT-PCR and ELISA. Treatment with GW9662, an...
read moreObstructive jaundice develops after occlusion of the common bile duct. Direct hyperbilirubinaemia, which occurs secondary to the condition, causes various life-threatening pathologies. Cytoprotective effects of Ganoderma lucidum (GL) have previously been shown. In this study, the effects of GL on oxidative stress and oxidant DNA damage in experimental obstructive jaundice were evaluated.
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