Prokaryotic expression, purification, and polyclonal antibody production of a hydrophobin from Grifola frondosa Zefang Wang1, Shuren Feng1, Yujian Huang1, Mingqiang Qiao1, Baohua Zhang2, and Haijin Xu2 1The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China 2The Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China Hydrophobins are small fungal proteins that...
read moreInfluence of Culinary-Medicinal Maitake Mushroom, Grifola frondosa (Dicks.: Fr.) S.F. Gray (Aphyllophoromycetideae) Polysaccharides on Gene Expression in Jurkat T Lymphocytes Natasa Radic,1* Zala Jevnikar,1 Natasa Obermajer,1,2 Jernej Kristl,1 Janko Kos,1,2 Franc Pohleven,3 & Borut Strukelj1,2 1Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, Slovenia; 2Department of Biotechnology, Jozef Stefan Institute, Slovenia; 3Biotechnical Faculty, University of Ljubljana, Slovenia ABSTRACT: The fruiting...
read moreMaitake Mushroom Extracts Ameliorate Progressive Hypertension and Other Chronic Metabolic Perturbations in Aging Female Rats Harry G. Preuss1~, Bobby Echard1, Debasis Bagchi2, Nicholas V. Perricone3 Georgetown University Medical Center, Department of Physiology, Washington, D.C. USA University of Houston College of Pharmacy, Department of Pharmacological and Pharmaceutical Services, Houston, TX 77204, USA Michigan State University College of Human Medicine, East Lansing, MI USA Abstract Objective: We assessed the ability of two...
read moreMaitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity Hong Lin • Elisa de Stanchina • Xi Kathy Zhou • Feng Hong • Andrew Seidman • Monica Fornier • Wei-Lie Xiao • Edward J. Kennelly • Kathleen Wesa • Barrie R. Cassileth • Susanna Cunningham-Rundles Maitake Abstract Bone marrow myelotoxicity is a major limitation of chemotherapy. While granulocyte colony stimulating factor (G-CSF) treatment is effective, alternative approaches to support...
read moreA polysaccharide extracted from Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine colon cancer Yuki Masuda • Koichi Ito • Morichika Konishi • Hiroaki Nanba Abstract We previously isolated the novel heteropolysaccharide maitake Z-fraction (MZF) from the maitake mushroom (Grifola frondosa), and demonstrated that MZF significantly inhibited tumor growth by inducing cell-mediated immunity. In this study, we demonstrated that MZF upregulated the...
read moreCommonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells Keith R Martin and Sara K Brophy Nutrition Program, Healthy Lifestyles Research Center, Arizona State University, USA Abstract Worldwide, over one million women will be newly diagnosed with breast cancer in the next year. Moreover, breast cancer is the second leading cause of cancer death in the USA. An accumulating body of evidence suggests that consumption of dietary mushrooms can protect against breast cancer. In this study,...
read moreBoth common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment Keith R Martin Abstract Background: Cardiovascular disease (CVD) is a leading cause of mortality in the United States as well as globally. Epidemiological studies show that regular fruit and vegetable consumption reduces CVD risk, in part, due to antioxidant activity and immunomodulation since oxidative stress and inflammation are features of atherogenesis. Accumulating...
read moreINORGANIC IODINE CONTENT OF COMMON, EDIBLE MUSHROOMS J. VETTER* Department of Botany, Faculty of Veterinary Science, Szent István University, Hungary The edible mushrooms have different valuable chemical properties (proteins, minerals, aromatic compounds, low lipid and energy contents, etc.) but there are practically no data about the iodine content. The aim of this work was to produce new data on the iodine content of the common edible mushrooms. The inorganic iodine contents of different wild growing (n=49) and cultivated (n=30) mushroom...
read moreGrifola frondosa ( Maitake ) water extract alleviates intestinal inflammation by suppressing TNF-α production and its signaling Jong Suk Lee1*, Su-Young Park1*, Dinesh Thapa1, Mi Kyoung Choi1, Ill-Min Chung2, Young-Joon Park3, Chul Soon Yong1, Han Gon Choi1 and Jung-Ae Kim1 1College of Pharmacy Yeungnam University, Korea 2College of Life and Environmental Sciences Konkuk University Seoul, Korea 3Research Center Samil Pharmaceutical Co. Ltd. Korea Abstract TNF-α is a major cytokine involved in inflammatory bowel disease (IBD). In this...
read morePotential Antitumor Activity of a Low-Molecular-Weight Protein Fraction from Grifola frondosa Through Enhancement of Cytokine Production Noriko Kodama,1,2 Shigeto Mizuno,3 Hiroaki Nanba,4 and Naoaki Saito1 1Laboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University; and Departments of 2Basic Educational Center for Pharmacy and 3Medical Pharmaceutics, 4Kobe Pharmaceutical University, Kobe, Japan ABSTRACT Edible mushrooms contain an abundance of immune-enhancing nutritients. Some of these compounds, referred to as...
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