Anti-fungal Cell Wall β-glucan Antibody in Animal Sera Ken-ichi Ishibashi, Chikaku Dogasaki, Masuro Motoi, Noriko Miura,Yoshiyuki Adachi, Naohito Ohno β-Glucan is a major component of the cell walls and pathogen-associated microbial patterns of fungi. We previously reported the presence of an antibody which reacts to β-glucan, anti-β-glucan (BG) antibody, in human sera. In livestock and domestic pets, the antibody’s response to fungal cell wall β-glucan is little understood. In this study, we examined the existence and...
read moreMaitake Mushroom (Grifola frondosa) Extract Induces Ovulation in Patients with Polycystic Ovary Syndrome: A Possible Monotherapy and a Combination Therapy After Failure with First-Line Clomiphene Citrate Jui-Tung Chen, MD, PhD, Kunihiko Tominaga, MD, DrPh, PhD, Yoshiaki Sato, MD, PhD,3Hideo Anzai, BS, BS, RPh, and Ryo Matsuoka, MD, PhD Abstract Background: Insulin resistance is a prominent feature of polycystic ovary syndrome (PCOS), and insulin-sensitizing drugs are used to induce ovulation. Recently, it was reported that an extract from...
read moreA Novel Lectin with Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Dried Fruiting Bodies of the Monkey Head Mushroom Hericium erinaceum (Lion’s Mane Mushroom) Yanrui Li,1 Guoqing Zhang, 1 Tzi Bun Ng,2 and Hexiang Wang, 1 ‘ State Key Laboratory for Agrobiotechnology, Department of Microbiology, China Agricultural University, China 2 School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong A lectin designated as Hericium erinaceum agglutinin (HEA) was...
read moreReduction of depression and anxiety by 4 weeks Lion’s Mane ( Hericium erinaceus ) intake Mayumi Nagano¹, Kuniyoshi Shimizu2, Ryuichiro Kondo2, Chickako Hayashi3, Daigo Sato4, Katsuyuki Kitagawa4, and Koichiro Ohnuki3 1Department of Clinical Psychology, Kyoto Bunkyo University, Japan 2 Faculty of Agriculture, Kyushu University, Japan 3 Kyushu-Eiyouhukushi University, Japan; and 4 Aso Biotech , Kawayo, Japan ABSTRACT Hericium erinaceus, a well known edible mushroom, has numerous biological activities. Especially...
read moreMedicinal uses of the mushroom Cordyceps militaris: Current state and prospects Shonkor Kumar Das, Mina Masuda, Akihiko Sakurai*, Mikio Sakakibara Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan ABSTRACT Cordyceps militaris is a potential harbour of bio-metabolites for herbal drugs and evidences are available about its applications for- revitalization of various systems of the body from ancient times. Amongst all the species, C. militaris is considered...
read moreHepatoprotective Effect of Syringic Acid and Vanillic Acid on Concanavalin A-Induced Liver Injury Ayano ITOH, Katsuhiro ISODA, Masuo KONDOH, Masaya KAWASE, Masakazu KOBAYASHI, Makoto TAMESADA, and Kiyohito YAGI The edible mushroom Lentinula edodes (shiitake) contains many bioactive compounds. In the present study, we cultivated L. edodes mycelia ( Shiitake ) in solid medium and examined the hot-water extract (L.E.M.) for its suppressive effect on concanavalin A (ConA)-induced liver injury in mice. ConA injection into the tail vein...
read moreGanoderma lucidum ( Reishi ) Protects Dopaminergic Neuron Degeneration Through Inhibition of Microglial Activation Ruiping Zhang, Shengli Xu, Yanning Cai, Ling Zhou, Xiaohong Zuo and Piu Chan Beijing Institute of Geriatrics and Department of Neurobiology and Neurology, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Xuanwu Hospital of Capital Medical University, China Abundant evidence has suggested that neuroinflammation participates in the pathogenesis of Parkinson’s disease (PD). The emerging evidence...
read moreAnti-oxidative effects of Phellinus linteus and red ginseng extracts on oxidative stress-induced DNA damage Byung-Jae Park, Yeong-Seok Lim, Hee-Jung Lee, Won Sik Eum, Jinseu Park, Kyu Hyung Han, Soo Young Choi& Kil Soo Lee Anti-oxidative effect of Phellinus linteus ( Meshima ) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. con CoIE1 plasmid DNA strands as well as nuclear DNA of it hepatocytes...
read moreThe effects of whole mushrooms during inflammation Sanhong Yu1, Veronika Weaver1, Keith Martin2 and Margherita T Cantorna*1 1Center for Immunology and Infectious Disease, Department of Veterinary and Biomedical Science, The Pennsylvania State University, USA and 2Department of Nutrition, Arizona State University, USA Abstract Background: Consumption of edible mushrooms has been suggested to improve health. A number of isolated mushroom constituents have been shown to modulate immunity. Five commonly consumed edible mushrooms were tested...
read moreMaitake Mushroom (Grifola frondosa): Systematic Review by the Natural Standard Research Collaboration Catherine Ulbricht, PharmD, Wendy Weissner, BA, Ethan Basch, MD, Nicole Giese, MS, Paul Hammerness, MD, Erica Rusie–Seamon, PharmD, Minney Varghese, BS, Jen Woods, BS The objective of this study was to evaluate the scientific evidence on maitake, including expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing. This review serves as a clinical support tool....
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