Reduction of depression and anxiety by 4 weeks Lion’s Mane ( Hericium erinaceus ) intake Mayumi Nagano¹, Kuniyoshi Shimizu2, Ryuichiro Kondo2, Chickako Hayashi3, Daigo Sato4, Katsuyuki Kitagawa4, and Koichiro Ohnuki3 1Department of Clinical Psychology, Kyoto Bunkyo University, Japan 2 Faculty of Agriculture, Kyushu University, Japan 3 Kyushu-Eiyouhukushi University, Japan; and 4 Aso Biotech , Kawayo, Japan ABSTRACT Hericium erinaceus, a well known edible mushroom, has numerous biological activities. Especially...
read moreMedicinal uses of the mushroom Cordyceps militaris: Current state and prospects Shonkor Kumar Das, Mina Masuda, Akihiko Sakurai*, Mikio Sakakibara Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan ABSTRACT Cordyceps militaris is a potential harbour of bio-metabolites for herbal drugs and evidences are available about its applications for- revitalization of various systems of the body from ancient times. Amongst all the species, C. militaris is considered...
read moreHepatoprotective Effect of Syringic Acid and Vanillic Acid on Concanavalin A-Induced Liver Injury Ayano ITOH, Katsuhiro ISODA, Masuo KONDOH, Masaya KAWASE, Masakazu KOBAYASHI, Makoto TAMESADA, and Kiyohito YAGI The edible mushroom Lentinula edodes (shiitake) contains many bioactive compounds. In the present study, we cultivated L. edodes mycelia ( Shiitake ) in solid medium and examined the hot-water extract (L.E.M.) for its suppressive effect on concanavalin A (ConA)-induced liver injury in mice. ConA injection into the tail vein...
read moreGanoderma lucidum ( Reishi ) Protects Dopaminergic Neuron Degeneration Through Inhibition of Microglial Activation Ruiping Zhang, Shengli Xu, Yanning Cai, Ling Zhou, Xiaohong Zuo and Piu Chan Beijing Institute of Geriatrics and Department of Neurobiology and Neurology, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Xuanwu Hospital of Capital Medical University, China Abundant evidence has suggested that neuroinflammation participates in the pathogenesis of Parkinson’s disease (PD). The emerging evidence...
read moreAnti-oxidative effects of Phellinus linteus and red ginseng extracts on oxidative stress-induced DNA damage Byung-Jae Park, Yeong-Seok Lim, Hee-Jung Lee, Won Sik Eum, Jinseu Park, Kyu Hyung Han, Soo Young Choi& Kil Soo Lee Anti-oxidative effect of Phellinus linteus ( Meshima ) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. con CoIE1 plasmid DNA strands as well as nuclear DNA of it hepatocytes...
read moreThe effects of whole mushrooms during inflammation Sanhong Yu1, Veronika Weaver1, Keith Martin2 and Margherita T Cantorna*1 1Center for Immunology and Infectious Disease, Department of Veterinary and Biomedical Science, The Pennsylvania State University, USA and 2Department of Nutrition, Arizona State University, USA Abstract Background: Consumption of edible mushrooms has been suggested to improve health. A number of isolated mushroom constituents have been shown to modulate immunity. Five commonly consumed edible mushrooms were tested...
read moreMaitake Mushroom (Grifola frondosa): Systematic Review by the Natural Standard Research Collaboration Catherine Ulbricht, PharmD, Wendy Weissner, BA, Ethan Basch, MD, Nicole Giese, MS, Paul Hammerness, MD, Erica Rusie–Seamon, PharmD, Minney Varghese, BS, Jen Woods, BS The objective of this study was to evaluate the scientific evidence on maitake, including expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing. This review serves as a clinical support tool....
read moreAntitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines KOHEI SHOMORI1, MAKO YAMAMOTO1, ICHIRO ARIFUKU2, KAZUKI TERAMACHI1 and HISAO ITO1 1Division of Organ Pathology, Department of Microbiology and Pathology, Faculty of Medicine,Tottori University, Japan 2Industrial Research Institute of Tottori Prefecture, Sakaiminato, Japan Abstract. We investigated the effects of a water-soluble extract of Maitake (Grifola frondosa), a Japanese edible mushroom, on the proliferation and cell death...
read moreMaitake Beta-Glucan Enhances Umbilical Cord Blood Stem Cell Transplantation in the NOD/SCID Mouse HONG LIN, ELISA DE STANCHINA, XI KATHY ZHOU, YUHONG SHE, DANTHANH HOANG, SANDY WY CHEUNG, BARRIE CASSILETH, AND SUSANNA CUNNINGHAM-RUNDLES Beta glucans are cell wall constituents of yeast, fungi and bacteria, as well as mushrooms and barley. Glucans are not expressed on mammalian cells and are recognized as pathogen-associated molecular patterns (PAMPS) by pattern recognition receptors (PRR). Beta glucans have potential activity as...
read moreMaitake beta-glucan enhances granulopoiesis and mobilization of granulocytes by increasing G-CSF production and modulating CXCR4/SDF-1 expression Koichi Ito, Yuki Masuda, Yoshihiko Yamasaki, Yoshinobu Yokota, Hiroaki Nanba Department of Microbial Chemistry, Kobe Pharmaceutical University, Japan Abstract Previous studies have presented that Maitake beta-glucan (MD-Fraction) extracted from the fruit body of Grifola frondosa has an anti-tumor effect by activating the immune system. Recently, the stimulating effects of beta-glucans on...
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