REFERENCES
[#2009-13] Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines, Kohei Shomori et al.
Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines KOHEI SHOMORI1, MAKO YAMAMOTO1, ICHIRO ARIFUKU2, KAZUKI TERAMACHI1 and HISAO ITO1 1Division of Organ Pathology, Department of Microbiology and Pathology, Faculty of Medicine,Tottori University, Japan 2Industrial Research Institute of Tottori Prefecture, Sakaiminato, Japan Abstract. We investigated the effects of a water-soluble extract of Maitake (Grifola frondosa), a Japanese edible mushroom, on the proliferation and cell death...
read more[#2009-12] Maitake Beta-Glucan Enhances Umbilical Cord Blood Stem Cell Transplantation in the NOD/SCID Mouse, Hong Lin et al.
Maitake Beta-Glucan Enhances Umbilical Cord Blood Stem Cell Transplantation in the NOD/SCID Mouse HONG LIN, ELISA DE STANCHINA, XI KATHY ZHOU, YUHONG SHE, DANTHANH HOANG, SANDY WY CHEUNG, BARRIE CASSILETH, AND SUSANNA CUNNINGHAM-RUNDLES Beta glucans are cell wall constituents of yeast, fungi and bacteria, as well as mushrooms and barley. Glucans are not expressed on mammalian cells and are recognized as pathogen-associated molecular patterns (PAMPS) by pattern recognition receptors (PRR). Beta glucans have potential activity as...
read more[#2009-11] Maitake beta-glucan enhances granulopoiesis and mobilization of granulocytes by increasing G-CSF production and modulating CXCR4/SDF-1 expression, Koichi Ito et al.
Maitake beta-glucan enhances granulopoiesis and mobilization of granulocytes by increasing G-CSF production and modulating CXCR4/SDF-1 expression Koichi Ito, Yuki Masuda, Yoshihiko Yamasaki, Yoshinobu Yokota, Hiroaki Nanba Department of Microbial Chemistry, Kobe Pharmaceutical University, Japan Abstract Previous studies have presented that Maitake beta-glucan (MD-Fraction) extracted from the fruit body of Grifola frondosa has an anti-tumor effect by activating the immune system. Recently, the stimulating effects of beta-glucans on...
read more[#2009-10] Characterization and Antitumor Effect of a Novel Polysaccharide from Maitake (Grifola frondosa), Yuki Masuda et al.
Characterization and Antitumor Effect of a Novel Polysaccharide from Maitake ( Grifola frondosa ) YUKI MASUDA,*,† AKIHISA MATSUMOTO,‡ TOSHIHIKO TOIDA,‡ TADAO OIKAWA,§KOICHI ITO,# AND HIROAKI NANBA† †Department of Microbial Chemistry, Kobe Pharmaceutical University, Japan, ‡Graduate School of Pharmaceutical Sciences, Chiba University, Japan, §Department of Life Science and Biotechnology, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Japan, and #Science 2 (G12), School of Medical Science, Gold Coast...
read more[#2009-09] Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy, Sensuke Konno
Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy Sensuke Konno Department of Urology, New York Medical College, Valhalla, NY, USA Abstract: Maitake D-fraction or PDF is the bioactive extract of maitake mushroom (Grifola frondosa) and its active constituent is the protein-bound polysaccharide (proteoglucan), or more specifically known as Beta-glucan. PDF has been extensively studied and a number of its medicinal potentials/properties have been unveiled and demonstrated. Those include...
read more[#2009-08] Maitake β-glucan enhances therapeutic effect and reduces myelosupression and nephrotoxicity of cisplatin in mice, Yuki Masuda et al.
Maitake β-glucan enhances therapeutic effect and reduces myelosupression and nephrotoxicity of cisplatin in mice Yuki Masuda a,*, Munechika Inoue a, Ayu Miyata a, Shigeto Mizuno b, Hiroaki Nanba a a Department of Microbial Chemistry, Kobe Pharmaceutical University, Japan b Department of Medical Pharmaceutics, Kobe Pharmaceutical University, Japan Cisplatin is broadly used clinically as an anticancer drug. Despite its significant anticancer activity, cisplatin induced nephrotoxicity and myelosuppression limit its use. MD-Fraction is...
read more[#2009-07] Possible disease remission in patient with invasive bladder cancer with D-fraction regimen, Srinivas Rajamahantry et al.
Possible disease remission in patient with invasive bladder cancer with D-fraction regimen Srinivas Rajamahanty, Brandon Louie, Cormac O’Neill, Muhammad Choudhury, Sensuke Konno Department of Urology, New York Medical College, Valhalla, New York, USA Abstract: Superficial bladder tumors are the most prevalent form of bladder cancers and transurethral resection is the primary surgical modality for those tumors. However, nearly 65% of patients will have tumor recurrence in five years while about 15% will have progression to muscle invasion....
read more[#2009-06] Synergistic potentiation of interferon activity with maitake mushroom D-fraction on bladder cancer cells, Brandon Louie et al.
Synergistic potentiation of interferon activity with maitake mushroom D-fraction on bladder cancer cells Brandon Louie, Srinivas Rajamahanty, John Won, Muhammad Choudhury and Sensuke Konno Department of Urology, New York Medical College, Valhalla, NY, USA To examine whether the combination of interferon (IFN)-α and maitake mushroom D-fraction (PDF), a bioactive mushroom extract, might potentiate the anticancer activity of IFN-α in bladder cancer T24 cells in vitro. IFN-α2B was able to induce a significant ( ≈ 50%) growth...
read more[#2009-05] A phase I/II trial of a polysaccharide extract from Maitake mushroom (Grifola frondosa) in breast cancer patients, Gary Deng et al.
A phase I/II trial of a polysaccharide extract from Maitake mushroom( Grifola frondosa) in breast cancer patients Gary Deng · Hong Lin · Andrew Seidman · Monica Fornier · Gabriella D’Andrea · Kathleen Wesa · Simon Yeung · Susanna Cunningham-Rundles · Andrew J. Vickers · Barrie Cassileth Abstract Background: Cancer patients commonly use dietary supplements to “boost immune function”. A polysaccharide extract from Grifola frondosa (Maitake extract) showed immunomodulatory effects in preclinical studies and therefore the...
read more[#2009-04] Improving Effects of the Mushroom Yamabushitake (Hericium erinaceus) on Mild Cognitive Impairment: A Double-blind Placebo-controlled Clinical Trial, Koichiro Mori et al.
Improving Effects of the Mushroom Yamabushitake (Hericium erinaceus) on Mild Cognitive Impairment: A Double-blind Placebo-controlled Clinical Trial Koichiro Mori1*, Satoshi Inatomi1, Kenzi Ouchi1, Yoshihito Azumi1 and Takashi Tuchida2 1Mushroom Laboratory, Hokuto Corporation, 800-8, Shimokomazawa, Nagano 2Isogo Central and Neurosurgical Hospital, , Yokohama, Japan A double-blind, parallel-group, placebo-controlled trial was performed on 50- to 80-year-old Japanese men and women diagnosed with mild cognitive impairment in order to...
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