REFERENCES
[#2006-07] Meshima: Kojima, Hiroyuki et al ‘Antitumor’
A Case of Spontaneous Regression of Hepatocellular Carcinoma with Multiple Lung Metastases Hiroyuki Kojima, Noboru Tanigawa, Shuji Kariya, Atsushi Komemushi, Yuzo Shomura, Satoshi Sawada, Eitatsu Arai, and Yoshiro Yokota Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. We present herein the case of a patient with hepatocellular carcinoma with multiple lung metastases in whom malignancy spontaneously regressed after taking Meshima (Phellinus linteus Mycelium). A 79year-old man consulted our hospital complaining...
read more[#2006-06] Immunomodulatory Properties of Grifola frondosa in Submerged Culture, Ming-Jiuan Wu et al.
Immunomodulatory Properties of Grifola frondosa in Submerged Culture Wu MJ(a), Cheng TL(b), Cheng SY(a), Lian TW(a), Wang LS(c), Chiou SY(d) a)Department of Biotechnology, Chia-Nan University of Pharmacy and Science, b)Taiwan Sugar Research Institute, c)Cheng-Kung University, d)Department of Health and Nutrition, Taiwan Maitake (Grifola frondosa) is a popular mushroom in Asia for its tasty flavor and immune- stimulating property. The aim of the study is to investigate the innate immunity augmentation effects of different extracts of mycelia...
read more[#2006-05] Lysophosphatidylethanolamine in Grifola frondosa as a neurotrophic activator via activation of MAP kinase, Atsuyoshi Nishina et al.
Lysophosphatidylethanolamine in Grifola frondosa as a neurotrophic activator via activation of MAP kinase Atsuyoshi Nishina, Hirokazu Kimura, Akihiro Sekiguchi, Ryo-hei Fukumoto, Satoshi Nakajima and Shoei Furukawa ABSTRACT We found that Maitake (Grifola frondosa) extracts induced activation of mitogen-activated protein kinase (MAPK) in cultured PC12 cells, a cell line of rat pheochromocytoma cells. The active substance was isolated by a few chromatographic steps including high-performance liquid chromatography, and was identified to be...
read more[#2006-04] Macrophage J774.1 cell is activated by MZ-Fraction (Klasma-MZ) polysaccharide in Grifola frondosa, Yuki Masuda et al.
Macrophage J774.1 cell is activated by MZ-Fraction (Klasma-MZ) polysaccharide in Grifola frondosa Masuda Y, Kodama N, Nanba H Department of Microbial Chemistry, Kobe Pharmaceutical University We previously reported that the (β-1,3)-branched (β-1,6)-glucan, MD-Fraction extracted from the fruit body of the edible maitake mushroom (Grifola frondosa) exhibits an antitumor effect. In this study, we separated a new polysaccharide from maitake, which we named Maitake MZ-Fraction (Klasma-MZ). MZ-Fraction is a β-glucan with a low molecular weight of...
read more[#2006-03] Maitake Miyake, Naomi et al. Low molecular weight maitake MD-Fraction (Klasma-MD) hydrolyzed with endo-β-1,6-glucanase of Trichoderma harzianum induces antitumor activities
Low molecular weight maitake MD-Fraction (Klasma-MD) hydrolyzed with endo-β-1,6-glucanase of Trichoderma harzianum induces antitumor activities Miyake N, Masuda Y, Murata Y, Inoue M, Matuda K, Okamoto K, Nanba H, Kodama N Department of Microbial Chemistry, Kobe Pharmaceutical University We previously reported that MD-Fraction (Klasma-MD), a specific-structured β-glucan extracted from fruit bodies of maitake mushrooms (Grifola frondosa), can activate cellular immune systems and express antitumor effects. The molecular weight of the...
read more[#2006-02] Maitake Gu, Chang-Qing et al. Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-α in HepG2 2.2.15
Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-α in HepG2 2.2.15 Gu CQ, Li JW, Chao FH Institute of Health and Environmental Medicine, PR China In this study, D-fraction extracted from Grifola frondosa ( GF-D from maitake ) and its combination with human interferon alpha-2b (IFN) were investigated for the inhibitory effect on hepatitis B virus (HBV) in HepG2 2.2.15 cells (2.2.15 cells). HBV DNA and viral antigens were analyzed by a quantitative real-time polymerase chain...
read more[#2006-01] Lion’s Mane Nagai, Kaoru et al Dilinoleoyl-phosphatidylethanolamine from Hericium erinaceum protects against ER stress-dependent Neuronal cell death via protein kinase C pathway
Dilinoleoyl-phosphatidylethanolamine from Hericium erinaceum protects against ER stress-dependent Neuronal cell death via protein kinase C pathway Kaoru Nagai a,*, Akiko Chibab, Toru Nishinoa, Takeo Kubotaa, Hirokazu Kawagishib,* aDepartment of Epigenetic Medicine, Interdisciplinary Graduate School ofMedicine and Engineering, University of Yamanashi, Yamanashi 409-3898, Japan bDepartment of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Shizuoka 422-8529, Japan Abstract In many types of neurodegeneration, neuronal...
read more[#2005-08] Enhancement of cytotoxicity of NK cells by D-Fraction, a polysaccharide from Grifola frondosa, Noriko Kodama et al.
Enhancement of cytotoxicity of NK cells by D-Fraction, a polysaccharide from Grifola frondosa Kodama N, Asakawa A, Inui A, Masuda Y, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University In innate immunity, activated natural killer (NK) cells attack and damage pathogens such as bacteria and virus without restriction by the MHC antigen. NK cells activated by IL-12 have been reported to recognize and kill tumor cells in perforin-mediated apoptosis. We have reported that D-Fraction, a polysaccharide extracted from the maitake...
read more[#2005-07] Tremella Mushroom, A Promising Material For Skincare Products, Y. Ohashi et al.
Tremella Mushroom, A Promising Material For Skincare Products Summary from: Y. Ohashi and Y. Yamamoto: Tremella fuciformis Polysaccharide. Fragrance Journal, 3, pp45-50 (2005) Abstract: “Glucuronoxylomannan (GXM)” is an acidic heteropolysaccharide extracted from Shiro-kikurage (Tremella fuciformis Berk). GXM has high water holding ability, and the value of water holding ability is higher than that of sodium hyaluronate So, GXM showed excellent moisturizing effect in a human use test. GXM also has good properties for cosmetics such...
read more[#2005-06] Poria Zhang, Lina Effect of Molecular Mass on Antitumor Activity of Heteropolysaccharide from Poria cocos
Effect of Molecular Mass on Antitumor Activity of Heteropolysaccharide from Poria cocos Lina ZHANG,IJ Li CHEN,’ Xi.a0jUall XU,1 Fanbo ZENG,2 and Peter Chi Keung CHEUNG3 IDepartment of Chemistry, Wuhan University, 2Tongji Medical College, Huazhong University of Science and Technology, 3Department of Biology, Chinese University of Hong Kong, Hong Kong A water-soluble heteropolysaccharide ac-PCMO from Poria cocos was successfully fractionated using a preparative size exclusion chromatography (SEC) column, and their weight-average...
read more