Characterization, Occurrence, and Molecular Cloning of a Lectin from Gnfola frondosa: Jacalin-Related Lectin of Fungal Origin Yoshiho NAGATA,l‘t Masako YAMASHITA,’ Hiroaki HONDA,’ JUT1k0 AKABANE,’ Koichi UEHARA,’ Akihiro SArro,1 Futoshi SumtsA,1 Kozo NISHIBORI,2 and Yasuo OODAIRA2 ‘Department of Bioresources Chemistry, Faculty of Horticulture, Chiba University, 2Section of Research and Development, Yukiguni-Maitake Co., Ltd. A lectin named GFL was isolated from the fruiting body of the basidiomycete...
read moreAre Botanical Glucans Effective in Enhancing Tumoricidal Cell Activity? Cunningham-Rundles S, Lin H, Cassileth B Department of Pediatrics, The Weill Medical College of Cornell University, New York, NY Studies of nutrient immune interactions have shown that protein calorie malnutrition and micronutrient deficiency impair immune development and immune response especially in critical phases of life. More recently, important data on the role of fatty acids in immune responses has emerged. The question of how or when dietary intervention might...
read moreMaitake D-Fraction enhances antitumor effects and reduces immunosuppression by mitomycin-C in tumor-bearing mice Kodama N, Murata Y, Asakawa A, Inui A, Hayashi M, Sakai N, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University OBJECTIVE: D-Fraction, a polysaccharide extracted from maitake mushrooms (Grifola frondosa), has been reported to exhibit an antitumor effect through activation of immunocompetent cells, including macrophages and T cells, with modulation of the balance between T-helper 1 and 2 cells. We examined...
read moreErinacine A increases catecholamine and nerve growth factor content in the central nervous system of rats Mari Shimbo, Hirokazu Kawagishi, Hidehiko Yokogoshi Abstract Nerve growth factor (NGF) is an essential protein for supporting growth and maintenance of peripheral sympathetic neurons. A novel diterpenoid erinacine, isolated from the cultured mycelia of Hericium erinacium ( lion’s mane ), is known to have a potent stimulating effect on NGF synthesis. The effects of erinacine and related compounds in the brain in vivo are not known. In...
read moreANTIMUTAGENIC ACTION OF LENTINULA EDODES AND AGARICUS BLAZEI ON ASPERGILLUS NIDULANS CONIDIA Edneia A. Souza-Paccola‘; Cleide A. Bomfeti2; Léia C.L. Fávaro2; Inês C.B. Fonseca‘; Luzia D. Paccola-Meirelles2* 1Departamento de Ciências Agrárias, Universidade Estadual de Londrina, Londrina, PR, Brasil 2Departamento de Ciências Biológicas, Universidade Estadual de Londrina,Londrina, PR, Brasil ABSTRACT The antimutagenic effect of the mushrooms Lentinula edodes ( Shiitake ) and Agaricus blazei was studied on conidia of...
read moreEffects of Ganoderma lucidum on Apoptotic and Anti-inflammatory Function in HT-29 Human Colonic Carcinoma Cells Kee-jong Hong, Dale M. Dunn, Chwan-Li Shen, Barbara C. Pence* Department of Pathology,TexasTechUniversityHealthSciencesCenter Ling Zhi extract (LZE) is a herbal mushroom preparation which been used world wide for the prevention and treatment of various cancers. The current study was designed to evaluate these claims in human colon cancer cells in terms of cancer preventive mechanisms. Results have demonstrated induction of apoptosis,...
read moreMedicinal Value of Culinary-Medicinal Maitake Mushroom Grifola frondosa (Dicks.:Fr.) S.F. Gray (Aphyllophoromycetideae). Review. Cun Zhuang and Solomon P Wasser ABSTRACT: Grifola frondosa (Maitake) is a culinary—medicinal mushroom found in some parts of Europe, North America, and Asia. It usually grows naturally on and around the roots of various kinds of deciduous trees. In Japan, it was found in the northern part, and wild G. frondosa was served only at top-class restaurants because of its good flavor, crisp texture, and excellent aroma....
read moreUsefulness of Anti-Cancer Complementary Immune Therapy with DVM Fraction Shimada, T(a), Shnidman, E(b), Shirota, M(b) a) Department of Veterinary Surgery, Osaka Prefecture University, Japan b) Maitake Products, Inc. D-fraction was used as a complementary therapy for dogs with cancer treated with conventional anti-cancer therapies (surgery and chemotherapy). Due to its appealing taste, the dogs did not offer any resistance to its long-term use. According to pet owners, in almost all cases it helped to maintain or improve the quality of life of...
read morePurification and Characterization of a Novel Prolyl Aminopeptidase from Maitake (Grifola frondosa) Kazuyuki HIWATASHI,1 Kazuyuki HoRI,I Keitaro TAKAHASHI,’ Akira KAGAYA,2 Shunzo INouE,2 Toshihiro SUGIYAMA,3 and Saori TAKAHASHIl‘t ‘Department of Bioengineering, Akita Research Institute of Food and Brewing,2Akita Jujo Chemicals Co., Ltd.3Department of Biochemistry, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan We have found a novel prolyl aminopeptidase in Maitake (Grifola frondosa). The...
read moreEffects of a Water-Soluble Bioactive Factor from Grifola frondosa, the Mushroom Maitake on Adipocyte Differentiation Katsuhiko MINAMINO, Yuri YANAGA, Hironori MASUI and Masaru OHTSURUDepartment of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women’s University, A bioactive factor inhibiting adipocyte differentiation was found in the water-soluble fraction of Maitake (Grifola frondosa). The fraction including bioactive factors was isolated by HPLC on Superdex Peptide HR 10/30. This water-soluble...
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