REFERENCES
[#2002-04] Maitake: Inoue, Atsuyuki et al ‘D-Fraction Immunity and Anti-tumor’
Effect of maitake (Grifola frondosa) D-fraction on the control of the T lymph node Th-1/Th-2 proportion Inoue A, Kodama N, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University We have already reported that the D-Fraction, a β-glucan extracted from the fruiting body of the maitake mushroom (Grifola frondosa), activates cellular immunity and expresses anti-tumor effects. In this study we investigated the anti-tumor functions of D-Fraction in relation to its control of the balance between T lymphocyte subsets Th-1 and Th-2....
read more[#2002-03] A polysaccharide, extract from Grifola frondosa, induces Th-1 dominant responses in carcinoma-bearing BALB/c mice, Noriko Kodama et al.
A polysaccharide, extract from Grifola frondosa, induces Th-1 dominant responses in carcinoma-bearing BALB/c mice Kodama N, Harada N, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University A polysaccharide, designated as the D-fraction, extracted from maitake (Grifola frondosa), was reported to have anti-tumor effects by activating macrophages and T cells in C3H/HeN mice in which a Th-1 dominant response was established. In this study using BALB/c mice in which a Th-2 response is genetically dominant, D-fraction reduced the...
read more[#2002-02] The Inducer of the Synthesis of Nerve Growth Factor From Lion’s Mane (Hericium erinaceus), Hirokazu Kawagishi et al.
The Inducer of the Synthesis of Nerve Growth Factor From Lion’s Mane (Hericium erinaceus) Hirokazu Kawagishi, Ph.D., Shoei Furukawa, Ph.D., Cun Zhuang, Ph.D., and Rika Yunoki Abstract Nerve growth factor (NGF) is closely related to Alzheimer’s dementia, and studies have suggested that the disease may be prevented or its symptoms may be improved when NGF is given into the brain directly. However, since NGF is a protein it usually cannot pass through the blood-brain barrier. Recently, researchers have targeted on the...
read more[#2002-01] Royal Agaricus, Mizuno, Takashi Medicinal Properties and Clinical Effects of Culinary-Medicinal Mushroom Agaricus Murrill (Agaricomycetideae) (Review)
Medicinal Properties and Clinical Effects of Culinary-Medicinal Mushroom Agaricus Murrill (Agaricomycetideae) (Review) Takashi Mizuno Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Japan ABSTRACT: Agaricus Hazel Murrill (“Kawariharatake” in Japan, “Cogmelo de Deus” in Brazil) was first discovered in Florida, USA, in 1944. Its main natural habitat is the mountainous district of Piedade in Sao Paulo, Brazil. It was found that the rate of occurrence of adult diseases in the...
read more[#2001-12] Cholesterol-lowering effects of maitake (Grifola frondosa) fiber, shiitake (Lentinus edodes) fiber, and enokitake (Flammulina velutipes) fiber in rats, M. Fukushima et al.
Cholesterol-lowering effects of maitake (Grifola frondosa) fiber, shiitake (Lentinus edodes) fiber, and enokitake (Flammulina velutipes) fiber in rats Fukushima M, Ohashi T, Fujiwara Y, Sonoyama K, Nakano M. Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine The effects of mushroom fibers on serum cholesterol and hepatic low-density lipoprotein (LDL) receptor mRNA in rats were investigated. Rats were fed a cholesterol-free diet with 50 g/kg cellulose powder (CP), 50 g/kg maitake (Grifola frondosa)...
read more[#2001-11] Maitake (Grifola frondosa) improve glucose tolerance of experimental diabetic rats, H. Horio et al.
Maitake (Grifola frondosa) improve glucose tolerance of experimental diabetic rats Horio H, Ohtsuru M. Department of Food Science and Nutrition, Faculty of Home Economics, Nishikyushu University We have previously reported that rats with diabetes induced by injecting streptozotocin into neonates showed remarkably lower blood glucose, urine volume, and glucosuria after administration of Maitake (Grifola frondosa). In the present study, we investigated the effects of Maitake on insulin concentration, organ weight, serum composition, and islets...
read more[#2001-10] Nitric oxide-mediated antitumor activity induced by the extract from Grifola frondosa (Maitake mushroom) in a macrophage cell line, RAW264.7, I. Sanzen et al.
Nitric oxide-mediated antitumor activity induced by the extract from Grifola frondosa (Maitake mushroom) in a macrophage cell line, RAW264.7 Sanzen I, Imanishi N, Takamatsu N, Konosu S, Mantani N, Terasawa K, Tazawa K, Odaira Y, Watanabe M, Takeyama M, Ochiai H. Dept. of Clinical Nursing, Faculty of Medicine, Toyama Medical and Pharmaceutical University We have investigated D-fraction (MDF) extracted from Grifola frondosa ( Maitake mushroom) on the inducible nitric oxide synthase (iNOS)-mediated nitric oxide (NO) production in RAW264.7 (RAW)...
read more[#2001-09] A Possible Hypoglycemic Effect of Maitake Mushroom on Type 2 Diabetes Patients, Sensuke Konno et al.
A Possible Hypoglycemic Effect of Maitake Mushroom on Type 2 Diabetes Patients Konno S, Tortorelis G, Fullerton SA, Samadi AA, Hettiarachchi J, Tazaki H Department of Urology, New York Medical College Two patients diagnosed with Type 2 diabetes had significantly elevated fasting blood glucose (FBG) levels even with administration of glibenclamide, a commonly-prescribed diabetes drug. Both patients were given Maitake mushroom caplets (500 mg) in daily doses, along with their glibenclamide, and experienced a sharp drop in blood glucose levels to...
read more[#2001-08] Maitake SX-Fraction: Possible Hypoglycemic Effect on Diabetes Mellitus, Sensuke Konno
Maitake SX-Fraction: Possible Hypoglycemic Effect on Diabetes Mellitus Sensuke Konno, Ph.D. Diabetes mellitus is a metabolic disorder characterized by persistent hyperglycemia affecting more than 16 million people in the United States and some 250 million people worldwide.1 The prevalence of diabetes is increasing by 4–5 percent every year with an estimated 40–45 percent of people over 65 years old at risk.2 To enhance peripheral insulin sensitivity, pharmaceuticals, such as troglitazone8 and metformin,9,10 have been used. Although...
read more[#2001-07] Th1/Th2-Balancing Immunomodulating Activity of Gel-Forming (1→3)- β-Glucans from Fungi Maitake, Yoko Suzuki et al.
Th1/Th2-Balancing Immunomodulating Activity of Gel-Forming (1→3)- β-Glucans from Fungi Maitake Yoko SUZUKI, Yoshiyuki ADACHI, Naohito OHNO, and Toshiro YADOMAE Laboratory of Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Japan The immunomodulating effects of various gel-forming (1→3)-β-glucans, grifolan (GRN), SSG, sonifilan (SPG) and alkaline-treated SPG (SPG-OH), on balancing helper T cell activity were examined in a murine model. Plasma from mice that were injected with GRN...
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