REFERENCES
[#1988-01] Blood Pressure-Lowering Activity Present in the Fruit Body of Grifola frondosa (Maitake), K. Adachi et al.
Blood Pressure-Lowering Activity Present in the Fruit Body of Grifola frondosa (Maitake) Adachi, K, Nanba, H, Otsuka, M, Kuroda, H Department of Microbiology, Kobe Women’s College of Pharmacy The fruit body of Grifola frondosa (maitake), Basidiomycetes, was confirmed to contain a substance with blood pressure-lowering activity. When powdered fruit body of maitake was given orally to spontaneously hypertensive rats (SHR), blood pressure reduction was observed, in contrast to the control group in which the blood pressure increased with...
read more[#1987-09] Effect of Shiitake (Lentinus edodes) and Maitake (Grifola frondosa) Mushrooms on Blood Pressure and Plasma Lipids of Spontaneously Hypertensive Rats, Y. Kabir et al.
Effect of Shiitake (Lentinus edodes) and Maitake (Grifola frondosa) Mushrooms on Blood Pressure and Plasma Lipids of Spontaneously Hypertensive Rats Kabir, Y, Yamaguchi, M, Kimura, S Laboratory of Nutrition, Department of Food Chemistry, Tohoku University To study the effect of Shiitake (Lentinus edodes) and Maitake (Grifola frondosa) on hypertension, spontaneously hypertensive rats were fed a diet containing 5% mushroom powder and 0.5% NaCl solution as drinking water for 9 weeks. The dietary mushrooms decreased the blood pressure. The plasma...
read more[#1987-08] Antitumor Activities of Edible Mushrooms by Oral Administration, K. Mori et al.
Antitumor Activities of Edible Mushrooms by Oral Administration Mori, K (a), Toyomasu, H (a), Nanba, H (b), Kuroda, H (b) a) The Mushroom Research Institute of Japan, b) Kobe Women’s College of Pharmacy Antitumor activities of edible mushrooms were investigated by breeding mice with the feed containing 10-30% (w/w) powdered fruit bodies. In allogeneic tumor systems (Sarcoma 180 in ICR mice), the tumor growth was suppressed to 40-50% by oral administration of edible mushrooms. While in syngeneic systems (B-16 melanoma or Lewis Lung...
read more[#1987-07] Host-mediated antitumor effect of grifolan NMF-5N, a polysaccharide obtained from Grifola frondosa (maitake), T. Takeyama et al.
Host-mediated antitumor effect of grifolan NMF-5N, a polysaccharide obtained from Grifola frondosa ( maitake ) Takeyama T, Suzuki I, Ohno N, Oikawa S, Sato K, Ohsawa M, Yadomae T. Tokyo College of Pharmacy The antitumor mechanism of grifolan NMF-5N, a β-1,3-glucan obtained from mycelia of Grifola frondosa, was examined. Grifolan NMF-5N did not show direct cytocidal effect on cultured tumor cells. However, intraperitoneal injection of grifolan NMF-5N increased the number of peritoneal exudate cells and peritoneal adherent cells which showed...
read more[#1987-06] ANTITUMOR EFFECT OF POLYSACCHARIDE GRIFOLAN NMF-5N ON SYNGENEIC TUMOR IN MICE, I. Suzuki et al.
ANTITUMOR EFFECT OF POLYSACCHARIDE GRIFOLAN NMF-5N ON SYNGENEIC TUMOR IN MICE IWAO SUZUKI,* TAKAHIRO TAKEYAMA,* NAOHITO OHNO,* SHOZO OIKAWA,** KICHIRO SATO,** YOSHIYUKI SUZUKI,** AND TOSHIRO YADOMAE* Tokyo College of Pharmacy, * Horinouchi, Hachioji, Tokyo, 192-03, Japan and Nippon Beet Sugar Mfg., Co. Ltd., ** Chuo-ku, Tokyo, 104, Japan Antitumor activity of grifolan (from maitake ) NMF-5N, a β-1,3-glucan obtained from mycelia of Grifola frondosa, was examined. Grifolan NMF-5N showed antitumor activities in allogeneic and syngeneic...
read more[[#1987-05] Conformational Changes of the Two Different Conformers of Grifolan in Sodium Hydroxide, Urea or Dimethylsulfoxide Solution, N. Ohno et al.
Conformational Changes of the Two Different Conformers of Grifolan in Sodium Hydroxide, Urea or Dimethylsulfoxide Solution Ohno, N (a), Adachi, Y(a), Ohsawa, M (b), Sato, K (b),Oikawa, S (b), Yadomae, T (b) a) Tokyo College of Pharmacy, b) Nippon Beet Sugar Mfg. Co. Ltd. Grifolan is an antitumor (1–>3)-β-D-glucan with a β-glucosyl substitution at C-6 of every three main chain units, and is produced by Grifola frondosa ( maitake ). Grifolan possesses two different solid-state conformations, N (native) and H (helix) (N. Ohno et al.,...
read more[#1987-02] Potentiation of Host-Mediated Antitumor Activity in Mice by Beta-Glucan Obtained from Grifola frondosa (Maitake), K. Adachi et al.
Potentiation of Host-Mediated Antitumor Activity in Mice by Beta-Glucan Obtained from Grifola frondosa (Maitake) Adachi, K, Nanba, H, Kuroda, H Department of Microbiology, Kobe Women’s College of Pharmacy A polysaccharide (3-branched β-1,6-glucan MT-2) extracted from fruit bodies of Grifola frondosa ( maitake ) showed an antitumor effect against mouse syngeneic tumors (MM-46 carcinoma and IMC-carcinoma). It not only directly activates various effector cells (macrophages, Natural Killer cells, killer T-cells, etc.) to attack tumor cells,...
read more[#1987-01] The Chemical Structure of an Antitumor Polysaccharide in Fruit Bodies of Grifola frondosa (Maitake), Hiroaki Nanba et al.
The Chemical Structure of an Antitumor Polysaccharide in Fruit Bodies of Grifola frondosa (Maitake) Nanba, H, Hamaguchi, A, Kuroda, H Laboratory of Microbiology, Kobe Women’s College of Pharmacy A polysaccharide was extracted from fruit bodies of Grifola frondosa ( maitake ), and the chemical structure and antitumor activity was studied. The extracted polysaccharide could be hydrolyzed by beta-glucanase into glucose, indicating it to be a beta-glucan. The sample gave methyl 2,3,4,6-tetra-O-methyl 2,4,6-tri-O-, methyl2,3,4-tri-O- and...
read more[#1986-09] Maitake: Ohno, Naohito et al ‘Phagocytic System’
Effect of Activation or Blockade of the Phagocytic System on the Antitumor Activity of Grifolan NAOHITO OHNO,a MAMI HAYASHI,a IWAO SUZUKI,a SHOZO OIKAWA,b KICHIRO SATO,b YOSHIYUKI Suzum,b and TOSHIRO YADOMAE” Tokyo College of Pharmacy,’ Horinouchi, Hachioji, Tokyo 192-03, Japan and Nippon Beet Sugar Mfg., Co., Ltd.,”Chuo-ku, Tokyo 104, Japan The effect of activation or blockade of the phagocytic system on the antitumor activity of grifolan (from maitake ) was investigated. The activity of grifolan was abrogated by treatment...
read more[#1986-08] Maitake and other mushrooms: Ohno, Naohito et al ‘Grifolan 5′
Carbon-13 Nuclear Magnetic Resonance Spectroscopy of Some Edible Mushrooms NAOHITO OHNO, IWAO SUZUKI, and TOSHIRO YADOMAE* Tokyo College of Pharmacy, Horinouchi, Hachioji, Tokyo 192-03, Japan In this paper, carbon-13 nuclear magnetic resonance (13C-NMR) spectra of some edible Mushrooms, Grifola frondosa ( maitake ), Lentinus edodes, Flammulina velutipes, Pholiota nameko, Agaricus bisporus, Lyophyllum cinerascens, Lyophyllum aggregatum, and Peziza vesiculosa, as aqueous suspensions were measured and the glucan compositions in these mushrooms...
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