[#2008-09] Bioactive Substance from Grif...

Bioactive Substance from Grifola frondosa (Maitake) Mushroom Inhibits CCAAT Enhancer Binding Protein β and δ Expression on C3H10T1/2 B2C1 Adipocyte Cells Katsuhiko MINAMINO, Yuri YANAGA and Masaru OHTSURU* Department of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women’s University, Nishinomiya 663-8558, Japan Summary Bioactive compound substances from Maitake (Grifola frondosa) inhibited adi­pocyte differentiation of B2C1 preadipocytes. This compound is not related to MAP kinase (ERK1 and ERK2) cascades or β-catenin, which...

[#2008-08] Inhibitory Effect of MD-Fract...

Inhibitory Effect of MD-Fraction on Tumor Metastasis: Involvement of NK Cell Activation and Suppression of Intercellular Adhesion Molecule (ICAM)-1 Expression in Lung Vascular Endothelial Cells Yuki MASUDA,*,a Yukihito MURATA,a Masahiko HAYASHI,b and Hiroaki NANBAa aDepartment of Microbial Chemistry, Kobe Pharmaceutical University and b Department of Pharmacy, Iwaki Meisei University The anti-metastatic activity of MD-Fraction extracted from the maitake mushroom (Grifola frondosa) was examined in an experimental murine model of lung metastasis. Intraperitoneal...

[#2008-07] Submerged culture mycelium an...

Submerged culture mycelium and broth of Grifola frondosa improve glycemic responses in diabetic rats. Lo HC, Hsu TH, Chen CY. Department of Medical Education and Research, Changhua Christian Hospital, Changhua, Taiwan. Grifola frondosa ( maitake ), an edible fungus with a large fruiting body and overlapping caps, has been demonstrated to be a natural source of health-promoting substances, mainly due to its polysaccharides β-glucan. By using male Wistar rats injected with saline (normal rats) or nicotinamide plus streptozotocin (diabetic rats), we investigated the effects...

[#2008-06] Grifola frondosa (Maitake Mus...

Grifola frondosa (Maitake Mushroom) Water Extract Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis Through Inhibition of Reactive Oxygen Species and Extracellular Signal-Regulated Kinase Phosphorylation Jong-Suk Lee,1 Byung Chul Park,1 Yu Jin Ko,1 Mi Kyoung Choi,1 Han Gon Choi,1 Chul Soon Yong,1 Jae-Sung Lee,2 and Jung-Ae Kim1 1College of Pharmacy and 2School of Food Technology and Food Service Industry, Yeungnam University, Gyeongsan, Republic of Korea ABSTRACT Grifola frondosa, a large edible mushroom also known as maitake, has been used as a health food...

[#2008-05] Possible immunotherapeutic po...

Possible immunotherapeutic potentiation with D-Fraction in prostate cancer cells Paul Pyo, Brandon Louie, Srinivas Rajamahanty, Muhammad Choudhury and Sensuke Konno* Department of Urology, New York Medical College   Abstract Background: Prostate cancer remains the most common malignancy among elderly men and the second leading cause of cancer death in the United States. Although several conventional therapies are currently available, they have a low efficacy and the more effective treatment modalities need to be established. Interferons (IFNs) are one of such options...

[#2007-11] Maitake Yang, Byung-Keun et a...

Chemical characteristics and immuno-modulating activities of exo-biopolymers produced by Grifola frondosa during submerged fermentation process Byung-Keun Yang, Young-Ah Gu, Yong-Tae Jeong, Hun Jeong, Chi-Hyun Song Abstract The immune-modulating activities and chemical characteristics of exo-biopolymer (EX-GF) produced by a submerged mycelial culture of Maitake (Grifola frondosa) were studied. The EX-GF was fractionated into EX-GF-Fr.1, II, and III by Sephadex G-100 gel chromatography. Anti-complementary activity of EX-GF-Fr. III was highest (71.1%) among them, and its...