[#2007-07] Enhancement of Umbilical Cord...

Enhancement of Umbilical Cord Blood Cell Hematopoiesis by Maitake Beta-Glucan Is Mediated by Granulocyte Colony-Stimulating Factor Production Lin H(a,b), Cheung SWY(b), Nesin M(b), Cassileth BR(a), Cunningham-Rundles S(b) a)Integrative Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York, b)Host Defenses Program, Department of Pediatrics, Cornell University Weill Medical College, New York, New York Maitake beta-glucan (MBG) is an extract from the fruit body of the Grifola frondosa mushroom that is being widely used to treat cancer in Asia. We have...

[#2007-06] Submerged Production and Char...

Submerged Production and Characterization of Grifola frondosa Polysaccharides – A New Application to Cosmeceuticals Sang Woo Kim, Hye Jin Hwang, Bum Chun Lee and Jong Won Yun Summary Grifola frondosa (maitake) is traditionally called ‘the king of mushrooms’ and ‘the hen of the woods’. Both the fruiting bodies and the mycelium of maitake have been reported to have antitumor and antiviral activities. Recently, submerged culture processes have been developed, with the intention of providing opportunities for increased economic exploita­tion of...

[#2007-05] Isolation, identification and...

Isolation, identification and function of a novel anti-HSV-1 protein from Grifola frondosa Gu CQ, Li JW, Chao FH, Jin M, Wang XW, Shen ZQ Institute of Environment and Health, PR China A novel antiviral protein was purified from an extract of Grifola frondosa ( maitake ) fruiting bodies using a procedure that included 40% ammonium sulfate precipitation and DEAE-cellulose ion exchange chromatography, and designated GFAHP. This protein inhibited herpes simplex virus type 1 (HSV-1) replication in vitro with an IC50 value of 4.1 μg/ml and a therapeutic index >29.3. Higher...

[#2007-04] Effect of various natural pro...

Effect of various natural products on growth of bladder cancer cells: two promising mushroom extracts. Konno S New York Medical College; Department of Urology, Valhalla, NY Despite the availability of several therapeutic options, a safer and more effective modality is urgently needed for treatment of bladder cancer. Specific immunotherapy is effective, but severe side effects limit its clinical use and underscore the need for unconventional therapies using less toxic substances. Many natural substances are touted for their medicinal aspects and side effect profiles, and...

[#2007-03] Induction of apoptosis in SGC...

Induction of apoptosis in SGC-7901 cells by polysaccharide-peptide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Cui FJ(a), Li Y(c), Xu YY(d), Liu ZQ(e), Huang DM(a), Zhang ZC(a), Tao WY(b) a)Institute of Bioengineering, School of Food and Biotechnology, Jiangsu University, b)Laboratory of Biopharmaceutics, School of Biotechnology, Southern Yangtze University, c)Department of Plant Science, North Dakota State University, Fargo, ND,d)Department of Cereal and Food Science, North Dakota State University, Fargo, ND, e)Institute of Bioengineering, Zhejiang...

[#2006-06] Immunomodulatory Properties o...

Immunomodulatory Properties of Grifola frondosa in Submerged Culture Wu MJ(a), Cheng TL(b), Cheng SY(a), Lian TW(a), Wang LS(c), Chiou SY(d) a)Department of Biotechnology, Chia-Nan University of Pharmacy and Science, b)Taiwan Sugar Research Institute, c)Cheng-Kung University, d)Department of Health and Nutrition, Taiwan Maitake (Grifola frondosa) is a popular mushroom in Asia for its tasty flavor and immune- stimulating property. The aim of the study is to investigate the innate immunity augmentation effects of different extracts of mycelia and culture filtrate from G....