[#1994-10] Antitumor Activity and Immuno...

Antitumor Activity and Immunological Property of Polysaccharides from the Mycelium of Liquid-Cultured Grifola frondosa Zhuang, C(a), Mizuno, T(b), Ito, H(c), Shimura, K(c), Sumiya, T(d), Kawade, M(d) a) The United Graduate School of Agricultural Sciences, Gifu University, b) Faculty of Agriculture, Shizuoka University, c) School of Medicine, Mie University, d) Iwade Mushroom Institute, Japan A systematic method for the fractionation and purification of antitumor polysaccharide fractions from the mycelium of liquid-cultured Grifola frondosa ( maitake ) was established....

[#1994-09] Fractionation and Antitumor A...

Fractionation and Antitumor Activity of Polysaccharides from Grifola frondosa Mycelium Zhuang, C, Mizuno, T, Ito, H, Shimura, K, Sumiya, T, Kawade, M The United Graduate School of Agricultural Sciences, Gifu University We developed a method for the fractionation and purification of antitumor polysaccharides, considered to be a type of immunopotentiator or BRM (biological response modifier), from the mycelium of liquid cultured Grifola frondosa ( maitake ). The active polysaccharide fractions that showed higher antitumor activity were considered to be heteroglycans or their...

[#1994-07] Maitake: Shimaoka, Iwao et al...

EFFECTS OF A COPPER-BINDING PEPTIDE FROM THE MUSHROOM GRIFOLA FRONDOSA ON INTESTINAL COPPER ABSORPTION Iwao Shimaoka, M.S.1*, Sachiko Ishiyama, B.S.2, Kohsuke Nishino, Ph.D.2, Yoshinori Itokawa, Ph.D.’ ‘Department of Environmental Medicine. Graduate Schoolof Medicine. KyotoUniversity, Kyoto, Japan2Department of Home Economics, Dohshisha Women’s College,Kyoto, Japan ABSTRACT The effect of a copper-binding peptide, purified previously from the fruit bodies of the mushroom, Grifola frondosa ( maitake ) , on copper absorption was investigated by using portal...

[#1994-06] Monoclonal antibody to proteo...

Monoclonal antibody to proteoglycan derived from Grifola frondosa (Maitake) Hirata A, Adachi Y, Itoh W, Komoda M, Tabata K, Sugawara I. Research Laboratory, Taito Co., Ltd. A murine monoclonal antibody (MAb) was prepared by immunizing BALB/c mice with a proteoglycan fraction derived from Grifola frondosa ( Maitake  mushroom), followed by the hybridization of spleen cells with mouse myeloma cells. The MAb (subclass; Ig G2b), designated MPG2, reacted with schizophyllan (SPG), curdlan, scleroglucan, laminarin and lentinan, but not with dextran, pullulan, mannan and xylan....

[#1994-05] Maitake – The King of M...

  Maitake – The King of Mushrooms Anthony J. Cichoke, MA, DC, DACBN For over 3,000 years, Traditional Chinese Medicine (TCM) has enjoyed an illustrious history. Today, TCM and Western medicine function side-by-side in Japan, as can be witnessed by the frequent use of maitake mushrooms to deal with conditions which, in the U.S., are usually treated with drugs. In Japan, maitake (pronounced my­tah-keh) mushrooms are highly prized both as food and medicine. People with serious degenerative illnesses travel long distances in search of the maitake mushroom....

[#1994-04] Enhancement of cytokine produ...

Enhancement of cytokine production by macrophages stimulated with (1->3)-beta-D-glucan, grifolan (GRN), isolated from Grifola frondosa Adachi Y, Okazaki M, Ohno N, Yadomae T. Laboratory of Immunopharmacology of Microbial Products, Tokyo University of Pharmacy and Life Science The ability of grifolan (GRN, maitake derived ), a purified fungal (1->3)-β-D-glucan, to induce various cytokines from macrophages was examined in vitro. Interleukin-6 (IL-6) activity in supernatants from the culture of macrophage cell line, RAW264.7 was dependent on increasing doses of GRN....