[#2012-04] Lion’s Mane Inanaga, Ka...

The current paper describes the physiological and nootropic actions of Amycenone, which is an activator of brain function that is obtained from extracts of the Yamabushitake (Hericium erinaceum). Kawagishi and his group have studied compounds that are derived from medicinal mushrooms and their use in the treatment of dementia since 1991. They have found that H. erinaceum exerts important bioactivities, including the induction of nerve growth factor (NGF) synthesis, the inhibition of the cytotoxicity of beta-amyloid peptide, and the protection against neuronal cell death...

[#2011-01] Effects of Hericium erinaceus...

Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice Koichiro MORI 2I, Yutaro OBARA2, Takahiro MORIYAI, Satoshi INATOMI2, and Norimichi NAKAHATA’ IDepartment of Cellular Signaling, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sen­dai 980-8578 and 2Mushroom Laboratory, 1-lokuto Corporation, 800-8 Shimokomazawa., Nagano 381-0008, Japan ABSTRACT The mushroom Hericium erinaceus ( Lion’s Mane ) has been used as a food and herbal medicine since ancient times in East...

[#2010-03] A Novel Lectin with Antiproli...

A Novel Lectin with Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Dried Fruiting Bodies of the Monkey Head Mushroom Hericium erinaceum (Lion’s Mane Mushroom) Yanrui Li,1 Guoqing Zhang, 1 Tzi Bun Ng,2 and Hexiang Wang, 1 ‘ State Key Laboratory for Agrobiotechnology, Department of Microbiology, China Agricultural University,  China 2 School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong   A lectin designated as Hericium erinaceum agglutinin (HEA) was isolated from dried fruiting...

[#2010-02] Reduction of depression and a...

Reduction of depression and anxiety by 4 weeks Lion’s Mane ( Hericium erinaceus ) intake Mayumi Nagano¹, Kuniyoshi Shimizu2, Ryuichiro Kondo2, Chickako Hayashi3, Daigo Sato4, Katsuyuki Kitagawa4, and Koichiro Ohnuki3 1Department of Clinical Psychology, Kyoto Bunkyo University, Japan  2 Faculty of Agri­culture, Kyushu University, Japan  3 Kyushu-Eiyouhukushi University, Japan; and  4 Aso Biotech , Kawayo, Japan   ABSTRACT Hericium erinaceus, a well known edible mushroom, has numerous biological activities. Especial­ly hericenones and erinacines isolated...

[#2009-04] Improving Effects of the Mush...

Improving Effects of the Mushroom Yamabushitake (Hericium erinaceus) on Mild Cognitive Impairment: A Double-blind Placebo-controlled Clinical Trial Koichiro Mori1*, Satoshi Inatomi1, Kenzi Ouchi1, Yoshihito Azumi1 and Takashi Tuchida2 1Mushroom Laboratory, Hokuto Corporation, 800-8, Shimokomazawa, Nagano 2Isogo Central and Neurosurgical Hospital, , Yokohama,  Japan   A double-blind, parallel-group, placebo-controlled trial was performed on 50- to 80-year-old Japanese men and women diagnosed with mild cognitive impairment in order to examine the efficacy of oral...

[#2008-04] Effect of Culinary-Medicinal ...

Effect of Culinary-Medicinal Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae), on Ethanol-Induced Gastric Ulcers in Rats Mahmood Ameen Abdulla,’,* Suzita Mohd Noor,’ Vikineswary Sabaratnam,2 Noorlidah Abdullah,2 Kah-Hui Wong,2 & Hapipah Mohd Ali3 ‘Department of Molecular Medicine, Faculty of Medicine, 2Institute of Biological Science, Faculty of Science, 3Department of Chemistry, Faculty of Science, University of Malaya ABSTRACT: The cytoprotective effect of Hericium erinaceus freeze-dried fruiting bodies was...