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BIORESEARCH UPDATE NEWS LETTER #1 Medici...

  Medicinal Mushrooms  For OPTIMUM HEALTH AND LONGEVITY  Ken Babal, C.N. We all know that vitamin and mineral supplements can augment diets by providing essential nutrients that ward off disease. Likewise, botanicals can help us stay well, and can be used medicinally. There is yet a third category that ranks high for cultivating optimum health and resistance to disease. This is the mushroom category. Mushrooms are members of the fungal family, sometimes referred to as the third kingdom. Being neither plant nor animal, they possess highly unique characteristics that...
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[#2011-10] ‘Anti-Hyperglycemic pr...

Anti-Hyperglycemic Properties of Crude Extract and Triterpenes from Poria cocos Tzu-Hsuan Li,1,2 Chia-Chung Hou,1 Cicero Lee-Tian Chang,3 and Wen-Chin Yang1,2,4,5 1Agricultural Biotechnology Research Center, Academia Sinica Taipei 115, Taiwan 2Department and Institute of Pharmacology, National Yang-Ming University Taipei 112, Taiwan 3Department of Veterinary Medicine, National Chung Hsing University Taichung, Taiwan 4Institute of Zoology, National Taiwan University Taipei 10617, Taiwan 5Department of Life Sciences, National Chung Hsing University Taichung,...
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[#2010-17] Immunomodulatory Effect of th...

Immunomodulatory Effect of the Polysaccharide-Rich Fraction from Sclerotium of Medicinal Mushroom Poria cocos F.A. Wolf (Aphyllophoromycetideae) on Balb/c Mice Chia-Yu Ma,1 Wan-Ching Chang,2 Hung-Min Chang,2 & James Swi-Bea Wu2,* 1Department of Food and Beverage Management, Technology and Science Institute of Northern Taiwan, Taipei City 112, Taiwan; 2Graduate Institute of Food Science and Technology, National Taiwan University, Taipei City 106, Taiwan   ABSTRACT: Dried sclerotia of medicinal mushroom Poria cocos F.A.Wolf were extracted with cold water. The...
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[#2008-16] Cytotoxic and Anti-oxidant Ac...

Cytotoxic and Anti-oxidant Activities of Lanostane-Type Triterpenes Isolated from Poria cocos Liang ZHOU, Yaochun ZHANG, Leslie Adell GAPTER,Hui LING, Rajesh AGARWAL,b and Ka-yun A new lanostane-type triterpene, 29-hydroxypolyporenic acid C (8), was isolated from the dried sclerotia of Poria cocos together with eight other known compounds pachymic acid (I), dehydropachymic acid (2), 3-acetyl­oxy-16a-hydroxytrametenolic acid (3), polyporenic acid C (4), 3-epi-dehydropachymic acid (5), 3-epi-dehydrotu­mulosic acid (6), tumulosic acid (7), and dehydrotumulosic acid (9). The...
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[#2005-06] Effect of Molecular Mass on A...

Effect of Molecular Mass on Antitumor Activity of Heteropolysaccharide from Poria cocos Lina ZHANG,IJ Li CHEN,’ Xi.a0jUall XU,1 Fanbo ZENG,2 and Peter Chi Keung CHEUNG3 IDepartment of Chemistry, Wuhan University, 2Tongji Medical College, Huazhong University of Science and Technology, 3Department of Biology, Chinese University of Hong Kong, Hong Kong   A water-soluble heteropolysaccharide ac-PCMO from Poria cocos was successfully fractionated using a preparative size exclusion chromatography (SEC) col­umn, and their weight-average molecular mass (Mw) was...
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[#2002-12] Dehydrotrametenolic Acid Indu...

Dehydrotrametenolic Acid Induces Preadipocyte Differentiation and Sensitizes Animal Models of Noninsulin-Dependent Diabetes Mellitus to Insulin Mayumi Sato, Takaaki Tai, Yoshiki Nunoura, Yukiko Yajima, Seiichi Kawashima and Keiji Tanaka We recently discovered that the triterpene acid compound dehydrotrametenolic acid promotes adipocyte dif­ferentiation in vitro and acts as an insulin sensitizer in vivo. This natural product has been isolated from dried sclerotia of Poria cocos WOLF (Polyporaceae), a well-known traditional Chinese medicinal plant. We examined the effects...