[#2013-16] Poria Cheng, Shujie et al. ...

Abstract. Poria cocos is a medicinal mushroom that is widely used in traditional Asian medicine. Here, we show that a characterized mixture of triterpenes extracted from P. cocos (PTE) and three purified triterpenes: pachymic acid (PA), dehydropachymic acid (DPA) and polyporenic acid C (PPAC) suppress the proliferation of the human pancreatic cancer cell lines Panc-1, MiaPaca-2, AsPc-1 and BxPc-3. Moreover, the most effective compound, PA, only slightly affects the proliferation of HPDE-6 normal pancreatic duct epithelial cells. The anti-proliferative effects of PTE on...

BIORESEARCH UPDATE NEWS LETTER #1 Medici...

  Medicinal Mushrooms  For OPTIMUM HEALTH AND LONGEVITY  Ken Babal, C.N. We all know that vitamin and mineral supplements can augment diets by providing essential nutrients that ward off disease. Likewise, botanicals can help us stay well, and can be used medicinally. There is yet a third category that ranks high for cultivating optimum health and resistance to disease. This is the mushroom category. Mushrooms are members of the fungal family, sometimes referred to as the third kingdom. Being neither plant nor animal, they possess highly unique characteristics that...

[#2011-10] Poria Li, Tzu-Hsuan et al. An...

Anti-Hyperglycemic Properties of Crude Extract and Triterpenes from Poria cocos Tzu-Hsuan Li,1,2 Chia-Chung Hou,1 Cicero Lee-Tian Chang,3 and Wen-Chin Yang1,2,4,5 1Agricultural Biotechnology Research Center, Academia Sinica Taipei 115, Taiwan 2Department and Institute of Pharmacology, National Yang-Ming University Taipei 112, Taiwan 3Department of Veterinary Medicine, National Chung Hsing University Taichung, Taiwan 4Institute of Zoology, National Taiwan University Taipei 10617, Taiwan 5Department of Life Sciences, National Chung Hsing University Taichung,...

[#2010-17] Poria Ma, Chia-Yu et al. Immu...

Immunomodulatory Effect of the Polysaccharide-Rich Fraction from Sclerotium of Medicinal Mushroom Poria cocos F.A. Wolf (Aphyllophoromycetideae) on Balb/c Mice Chia-Yu Ma,1 Wan-Ching Chang,2 Hung-Min Chang,2 & James Swi-Bea Wu2,* 1Department of Food and Beverage Management, Technology and Science Institute of Northern Taiwan, Taipei City 112, Taiwan; 2Graduate Institute of Food Science and Technology, National Taiwan University, Taipei City 106, Taiwan   ABSTRACT: Dried sclerotia of medicinal mushroom Poria cocos F.A.Wolf were extracted with cold water. The...

[#2008-16] Poria Zhou, Liang et al. Cyt...

Cytotoxic and Anti-oxidant Activities of Lanostane-Type Triterpenes Isolated from Poria cocos Liang ZHOU, Yaochun ZHANG, Leslie Adell GAPTER,Hui LING, Rajesh AGARWAL,b and Ka-yun A new lanostane-type triterpene, 29-hydroxypolyporenic acid C (8), was isolated from the dried sclerotia of Poria cocos together with eight other known compounds pachymic acid (I), dehydropachymic acid (2), 3-acetyl­oxy-16a-hydroxytrametenolic acid (3), polyporenic acid C (4), 3-epi-dehydropachymic acid (5), 3-epi-dehydrotu­mulosic acid (6), tumulosic acid (7), and dehydrotumulosic acid (9). The...

[#2005-06] Poria Zhang, Lina Effect of M...

Effect of Molecular Mass on Antitumor Activity of Heteropolysaccharide from Poria cocos Lina ZHANG,IJ Li CHEN,’ Xi.a0jUall XU,1 Fanbo ZENG,2 and Peter Chi Keung CHEUNG3 IDepartment of Chemistry, Wuhan University, 2Tongji Medical College, Huazhong University of Science and Technology, 3Department of Biology, Chinese University of Hong Kong, Hong Kong   A water-soluble heteropolysaccharide ac-PCMO from Poria cocos was successfully fractionated using a preparative size exclusion chromatography (SEC) col­umn, and their weight-average molecular mass (Mw) was...