[#2002-12] Poria Sato, Mayumi et al. Deh...

Dehydrotrametenolic Acid Induces Preadipocyte Differentiation and Sensitizes Animal Models of Noninsulin-Dependent Diabetes Mellitus to Insulin Mayumi Sato, Takaaki Tai, Yoshiki Nunoura, Yukiko Yajima, Seiichi Kawashima and Keiji Tanaka We recently discovered that the triterpene acid compound dehydrotrametenolic acid promotes adipocyte dif­ferentiation in vitro and acts as an insulin sensitizer in vivo. This natural product has been isolated from dried sclerotia of Poria cocos WOLF (Polyporaceae), a well-known traditional Chinese medicinal plant. We examined the effects...

[#1997-07] Poria Cuellar, Maria Jesus e...

Effect of the Basidiomycete Poria cocos on Experimental Dermatitis and Other Inflammatory Conditions Maria Jesus CUELLAR, Rosa Maria GINER, Maria del Carmen RECIO, Maria Jose JUST, Salvador MANEZ,* and Jose Luis Rios Departament de Farmacologia, Facultat de Farmacia, Universitat de Valencia, Valencia, Spain. The hydroalcoholic extract from Poria cocos was examined for oral and topical anti-inflammatory activities. It proved to be active against carrageenan, arachidonic acid, tetradecanoyl phorbol acetate (TPA) acute edemas, TPA chronic inflammation and oxazolone delayed...

[#1996-03] Poria Nukaya, Haruo et al. Is...

Isolation of Inhibitors of TPA-Induced Mouse Ear Edema from Hoelen, Poria cocos Haruo NUKAYA, Hirokazu YAMASHIRO, Hirotatsu FUKAZAWA, Hitoshi ISHIDA, and Kuniro TSUJI School of Pharmaceutical Sciences, University of Shizuoka, Japan. Several anti-inflammatory substances are known to inhibit the action of tumor promoters in two-stage mouseskin carcinogenesis.”) Since anti-inflammatory activity may play an important role in the mechanism of anti-tumor promotion, we have searched for new anti-inflammatory substances among natural products. In this study, inhibitory...

[#1992-01] Poria Hattori, Tomohisa et al...

Effect of Pachyman, a Main Component of Poria Cocos Wolf on Original-Type Anti-GBM Nephritis in Rats and Its Mechanisms Tomohisa Hattori, Kazumi Hayashi, Toshiyuki Nagao, Kazuya Furuta, Mikio Ito and Yoshio Suzuki Department of Pharmacology, Faculty of Pharmacy, Meijo University, Tenpaku-ku, Nagoya 468, Japan ABSTRACT—The antinephritic effect of pachyman on original-type anti-GBM nephritis in rats was in­vestigated. Pachyman was given to original-type anti-GBM nephritic rats for 10 days from the day of anti-GBM serum injection. Pachyman prevented urinary protein...