[#2002-17] Maitake Manohar, V. Effects o...

Effects of a water-soluble extract of maitake mushroom on circulating glucose/insulin concentrations in KK mice Manohar V, Talpur NA, Echard BW, Lieberman S, Preuss HG. Department of Physiology, Georgetown University Medical Center AIM: We examined benefits of a water-soluble extract of maitake mushroom designated as Fraction X (FXM) on the glucose/insulin metabolism of insulin-resistant KK mice, and compared the results of FXM with those of a sulphonylurea, Glipizide. DESIGN: In several acute studies, insulin-resistant KK mice were gavaged with a single dose of varying...

[#2002-09] Effects of Maitake mushroom f...

Effects of Maitake mushroom fractions on blood pressure of Zucker fatty rats Talpur N, Echard B, Dadgar A, Aggarwal S, Zhuang C, Bagchi D, Preuss HG. Department of Physiology, Medicine and Pathology, Georgetown University Medical Center A link exists between insulin resistance and many chronic disorders of aging including advancing-age. A safer means to prevent or, at least, slow the erosion of insulin sensitivity would provide a novel approach to better health. We compared the ability of a specific extract labeled fraction SX, as well as whole Maitake powder, fraction ES...

[#2002-08] Antihypertensive and metaboli...

Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains Talpur NA, Echard BW, Fan AY, Jaffari O, Bagchi D, Preuss HG. Department of Physiology and Biophysics, Georgetown University Medical Center Maitake mushroom has been reported to favorably influence hypertension and diabetes mellitus. The purpose of this study was to compare the effects of whole Maitake mushroom powder and two extracts designated as ether soluble (ES) and water soluble (WS) on Zucker fatty rats (ZFR), a model of insulin resistance, and on...

[#2001-11] Maitake (Grifola frondosa) im...

Maitake (Grifola frondosa) improve glucose tolerance of experimental diabetic rats Horio H, Ohtsuru M. Department of Food Science and Nutrition, Faculty of Home Economics, Nishikyushu University We have previously reported that rats with diabetes induced by injecting streptozotocin into neonates showed remarkably lower blood glucose, urine volume, and glucosuria after administration of Maitake (Grifola frondosa). In the present study, we investigated the effects of Maitake on insulin concentration, organ weight, serum composition, and islets of Langerhans in...

[#2001-09] A Possible Hypoglycemic Effec...

A Possible Hypoglycemic Effect of Maitake Mushroom on Type 2 Diabetes Patients Konno S, Tortorelis G, Fullerton SA, Samadi AA, Hettiarachchi J, Tazaki H Department of Urology, New York Medical College Two patients diagnosed with Type 2 diabetes had significantly elevated fasting blood glucose (FBG) levels even with administration of glibenclamide, a commonly-prescribed diabetes drug. Both patients were given Maitake mushroom caplets (500 mg) in daily doses, along with their glibenclamide, and experienced a sharp drop in blood glucose levels to within the normal range....

[#2001-08] Maitake SX-Fraction: Possible...

Maitake SX-Fraction: Possible Hypoglycemic Effect on Diabetes Mellitus Sensuke Konno, Ph.D. Diabetes mellitus is a metabolic dis­order characterized by persistent hyperglycemia affecting more than 16 million people in the United States and some 250 million people worldwide.1 The prevalence of diabetes is increasing by 4–5 percent every year with an estimated 40–45 percent of people over 65 years old at risk.2 To enhance peripheral insulin sensitivi­ty, pharmaceuticals, such as troglitazone8 and metformin,9,10 have been used. Although improved glycemic control with...