Usefulness of Anti-Cancer Complementary Immune Therapy with DVM Fraction Shimada, T(a), Shnidman, E(b), Shirota, M(b) a) Department of Veterinary Surgery, Osaka Prefecture University, Japan b) Maitake Products, Inc. D-fraction was used as a complementary therapy for dogs with cancer treated with conventional anti-cancer therapies (surgery and chemotherapy). Due to its appealing taste, the dogs did not offer any resistance to its long-term use. According to pet owners, in almost all cases it helped to maintain or improve the quality of life of...
read morePurification and Characterization of a Novel Prolyl Aminopeptidase from Maitake (Grifola frondosa) Kazuyuki HIWATASHI,1 Kazuyuki HoRI,I Keitaro TAKAHASHI,’ Akira KAGAYA,2 Shunzo INouE,2 Toshihiro SUGIYAMA,3 and Saori TAKAHASHIl‘t ‘Department of Bioengineering, Akita Research Institute of Food and Brewing,2Akita Jujo Chemicals Co., Ltd.3Department of Biochemistry, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan We have found a novel prolyl aminopeptidase in Maitake (Grifola frondosa). The...
read moreEffects of a Water-Soluble Bioactive Factor from Grifola frondosa, the Mushroom Maitake on Adipocyte Differentiation Katsuhiko MINAMINO, Yuri YANAGA, Hironori MASUI and Masaru OHTSURUDepartment of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women’s University, A bioactive factor inhibiting adipocyte differentiation was found in the water-soluble fraction of Maitake (Grifola frondosa). The fraction including bioactive factors was isolated by HPLC on Superdex Peptide HR 10/30. This water-soluble...
read moreMaitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro Lin H, She YH, Cassileth BR, Sirotnak F, Cunningham Rundles S. Integrative Medicine Service, Memorial Sloan-Kettering Cancer Center Previous studies have indicated that MD-fraction (MDF), in which the active component is beta 1,6-glucan with beta 1,3-branches, has anti-tumor activity as an oral agent and acts as an immune adjuvant. Since some other beta glucans appear to promote mobilization of hematopoietic stem cells, the effects...
read moreSafety of Maitake D-Fraction in Healthy Patients Glauco, S(a), Jano, F(a), Paolo, G(a), Konno, S(b) a) Practicing Physicians in Italy b) New York Medical College Both in vivo and in vitro studies and limited clinical trials thus far support a potent immunostimulatory, anticancer or antitumor as well as apoptosis-inducing activity for D-fraction, which may have great potential for cancer treatment and prevention. However, information on the safety of D-fraction or actual positive or negative effects of D-fraction on healthy human subjects had...
read morePotential growth inhibitory effect of maitake D-fraction on canine cancer cells Konno S. Department of Urology, New York Medical College The postulated anticancer effect of D-fraction, the bioactive extract of maitake mushroom, on three types (CF33, CF21, and CL-1) of canine cancer cells was evaluated. The effect of D-fraction on several human cancer cells was also investigated. The effect of other β-glucan products was likewise examined. D-fraction was highly effective on the canine cancer cells, either potently inhibiting cell growth or...
read moreAdministration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice Kodama N, Murata Y, Nanba H. Department of Microbial Chemistry, Kobe Pharmaceutical University We have reported that D-Fraction, a polysaccharide extracted from the edible maitake mushroom (Grifola frondosa), activates immunocompetent cells, thereby eliciting antitumor activity. To extend the application of D-Fraction as a nutritional supplement for healthy people as well as treatment for those with cancer, we investigated the effects of...
read moreThe Anti-Dementia Effect of Lion’s Mane Mushroom(Hericium erinaceum) and Its Clinical Application by Hirokazu Kawagishi, Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University Introduction Medicinal Mushrooms have become a hot item in the mass media in the last few years but the information being disseminated about them is not always scientifically accurate. Most of the studies on the efficacy of medicinal mushrooms that are available to the public are based on animal studies (usually in mice) or...
read moreMedicinal Value of Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilat (Aphyllophoromycetideae). A Literature Review* Christopher R. Hobbs Institute for Natural Products Research, Davis, California, USA ABSTRACT: Trametes (= Coriolus ) versicolor (L.:Fr.) Pilat, is a small, flexible polypore fungus that is an important part of the forest ecology as a recycler of dead and dying trees in forests throughout the world. Of all the mushrooms used today for their medicinal qualities, more research has been performed on this species than any other,...
read moreChaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay Yoo Kyoung Parka,**, Hyang Burm Leeb,c,**, Eun-Jae Jeona, Hack Sung Jungb and Myung-Hee Kanga,* aDepartment ofMedical Nutrition, Kyunghee University, South Korea bDepartment ofFood and Nutrition, Hannam University, Korea cSchool ofBiological Sciences, Seoul National University, Korea Abstract. The Chaga mushroom (Inonotus obliquus) is claimed to have beneficial properties for human health, such as anti-bacterial, anti-allergic,...
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