[#2012-03] Maitake Preuss, Harry G. et a...

   Fraction SX of Maitake Mushroom Favorably Influences Blood Glucose Levels and Blood Pressure in Streptozotocin-Induced Diabetic Rats  Harry G. Preuss; Bobby Echard,1 Jia Fu,1 Nicholas V. Perricone2, Debasis Bagchi,3 Mark Kaylor4, and Cun Zhuang4 ‘Department of Biochemistry, Georgetown University Medical Center, Washington, District of Columbia, USA. 2Michigan State University College of Human Medicine, East Lansing, Michigan, USA. 3Department of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, Houston, Texas,...

[#2011-06] Maitake Kunihiko Tominaga et ...

  ABSTRACT This study aimed to determine the effects of an extract from Maitake mushroom (“SX-fraction”, SX) on ovulation in patients with polycystic ovary syndrome (PCOS). Thirty patients were randomly assigned to either of the following two treatment arms for three months: the SX group (n = 15), which prescribed 207 mg/day of SX, and the control group (n = 15), which received 7.5 g/day of Shakuyaku-Kanzo-To (SKT; a Chinese herbal medicine). Ovulation was judged by the change of basal body temperature and ultrasonography. During the treatment period, 66.7% of the...

[#2010-13] Maitake Mushroom Extracts Ame...

Maitake Mushroom Extracts Ameliorate Progressive Hypertension and Other Chronic Metabolic Perturbations in Aging Female Rats Harry G. Preuss1~, Bobby Echard1, Debasis Bagchi2, Nicholas V. Perricone3 Georgetown University Medical Center, Department of Physiology, Washington, D.C. USA University of Houston College of Pharmacy, Department of Pharmacological and Pharmaceutical Services, Houston, TX 77204, USA Michigan State University College of Human Medicine, East Lansing, MI  USA   Abstract Objective: We assessed the ability of two commercially-available fractions...

[#2010-04] Maitake Mushroom (Grifola fro...

Maitake Mushroom (Grifola frondosa) Extract Induces Ovulation in Patients with Polycystic Ovary Syndrome: A Possible Monotherapy and a Combination Therapy After Failure with First-Line Clomiphene Citrate Jui-Tung Chen, MD, PhD, Kunihiko Tominaga, MD, DrPh, PhD, Yoshiaki Sato, MD, PhD,3Hideo Anzai, BS, BS, RPh, and Ryo Matsuoka, MD, PhD Abstract Background: Insulin resistance is a prominent feature of polycystic ovary syndrome (PCOS), and insulin-sen­sitizing drugs are used to induce ovulation. Recently, it was reported that an extract from Maitake mushroom (Grifola...

[#2007-10] Enhanced insulin-hypoglycemic...

Enhanced insulin-hypoglycemic activity in rats consuming a specific glycoprotein extracted from maitake mushroom Preuss HG, Echard B, Bagchi D, Perricone NV, Zhuang C Department of Physiology, Georgetown University Medical Center Aim: Intraperitoneal glucose tolerance (ipGTT) and insulin challenge (ICT) tests were implemented to evaluate whether a specific glycoprotein extract of maitake mushroom (Grifola frondosa) known as SX-fraction enhances insulin sensitivity in spontaneously hypertensive rats (SHR). Methods: SHR were divided randomly into a control group, a group...

[#2003-04] Maitake Talpur, Nadeem et al ...

Effects of niacin-bound chromium, Maitake mushroom fraction SX and (-)-hydroxycitric acid on the metabolic syndrome in aged diabetic Zucker fatty rats Talpur N, Echard BW, Yasmin T, Bagchi D, Preuss HG. Department of Physiology and Biophysics, Georgetown University Medical Center Previous studies in our laboratories have demonstrated that niacin-bound chromium (NBC), Maitake mushroom and (-)-hydroxycitric acid (HCA-SX) can ameliorate hypertension, dyslipidemias and diabetes mellitus, and therefore may be useful in weight management. In the present study, we used aged,...