REFERENCES

[#2007-12] Meshima Matsuba, Shintaro et al. Phellinus linteus Extract Augments the Immune Response in Mitomycin C-Induced Immunodeficient Mice

Phellinus linteus is a fungus distributed throughout Japan, Korea and China. Boiled watersoluble extracts from P. linteus (PLW) have shown anti-tumor and immunomodulatory properties in experiments done by intraperitoneal treatment, or in in vitro cell cultures. This is the first investigation on how oral administration of PLW influences immune responses. Here, we established immunodeficient mice by mitomycin C (MMC) and then researched how PLW influenced plaque-forming cell (PFC) production and populations of cytokine [interferon-(IFNg-)...

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[#2007-11] Maitake Yang, Byung-Keun et al. Chemical Characteristics and immuno-modulating activities of exo-biopolymers produced by Grifola frondosa during submerged fermentation process

Chemical characteristics and immuno-modulating activities of exo-biopolymers produced by Grifola frondosa during submerged fermentation process Byung-Keun Yang, Young-Ah Gu, Yong-Tae Jeong, Hun Jeong, Chi-Hyun Song Abstract The immune-modulating activities and chemical characteristics of exo-biopolymer (EX-GF) produced by a submerged mycelial culture of Maitake (Grifola frondosa) were studied. The EX-GF was fractionated into EX-GF-Fr.1, II, and III by Sephadex G-100 gel chromatography. Anti-complementary activity of EX-GF-Fr. III was highest...

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[#2007-10] Enhanced insulin-hypoglycemic activity in rats consuming a specific glycoprotein extracted from maitake mushroom, H Preuss et al.

Enhanced insulin-hypoglycemic activity in rats consuming a specific glycoprotein extracted from maitake mushroom Preuss HG, Echard B, Bagchi D, Perricone NV, Zhuang C Department of Physiology, Georgetown University Medical Center Aim: Intraperitoneal glucose tolerance (ipGTT) and insulin challenge (ICT) tests were implemented to evaluate whether a specific glycoprotein extract of maitake mushroom (Grifola frondosa) known as SX-fraction enhances insulin sensitivity in spontaneously hypertensive rats (SHR). Methods: SHR were divided randomly...

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[#2007-09] Stimulating Effects of Grifola frondosa (Maitake) on human osteoblastic cell cultures, A Saif et al.

Stimulating Effects of Grifola frondosa (Maitake) on human osteoblastic cell cultures Saif A, Lindequist U, Wende K Institute of Pharmacy, Ernst-Moritz-Arndt University Greifswald The effect of Grifola frondosa (GF – maitake ) total water extract on two osteoblastic cell cultures (HOS58 and SaOS-2) was investigated to determine if this edible medicinal mushroom has osteoinductive properties. The activity of alkaline phosphate and mineralization were used as indicators for the vitality and maturation of bone cells. The cultivation of...

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[#2007-08] Mushroom-Derived D-fraction as Single Agent for the Treatment of Lymphoma in Dogs, P.C. Griessmayr et al.

Mushroom-Derived D-fraction as Single Agent for the Treatment of Lymphoma in Dogs P.C. Griessmayr, M. Gauthier, L.G. Barber, and S.M. Cotter Background: D-fraction for Pet is a standardized essence extracted from the mushroom Maitake (Grifola frondosa) that has antitumor activity in tumor-bearing mice. In addition, D-fraction induces apoptosis in human prostate and bladder cancer cells and suppresses the proliferation in vitro of several canine tumor cell lines, such as lymphoma (C1-1), mammary gland (CF33), and connective tissue...

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[#2007-07] Enhancement of Umbilical Cord Blood Cell Hematopoiesis by Maitake Beta-Glucan Is Mediated by Granulocyte Colony-Stimulating Factor Production, Hong Lin et al.

Enhancement of Umbilical Cord Blood Cell Hematopoiesis by Maitake Beta-Glucan Is Mediated by Granulocyte Colony-Stimulating Factor Production Lin H(a,b), Cheung SWY(b), Nesin M(b), Cassileth BR(a), Cunningham-Rundles S(b) a)Integrative Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York, b)Host Defenses Program, Department of Pediatrics, Cornell University Weill Medical College, New York, New York Maitake beta-glucan (MBG) is an extract from the fruit body of the Grifola frondosa mushroom that is being widely used to...

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[#2007-06] Submerged Production and Characterization of Grifola frondosa Polysaccharides – A New Application to Cosmeceuticals, Sang Woo Kim et al.

Submerged Production and Characterization of Grifola frondosa Polysaccharides – A New Application to Cosmeceuticals Sang Woo Kim, Hye Jin Hwang, Bum Chun Lee and Jong Won Yun Summary Grifola frondosa (maitake) is traditionally called ‘the king of mushrooms’ and ‘the hen of the woods’. Both the fruiting bodies and the mycelium of maitake have been reported to have antitumor and antiviral activities. Recently, submerged culture processes have been developed, with the intention of providing opportunities for increased...

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[#2007-05] Isolation, identification and function of a novel anti-HSV-1 protein from Grifola frondosa, Chang-Qing Gu et al.

Isolation, identification and function of a novel anti-HSV-1 protein from Grifola frondosa Gu CQ, Li JW, Chao FH, Jin M, Wang XW, Shen ZQ Institute of Environment and Health, PR China A novel antiviral protein was purified from an extract of Grifola frondosa ( maitake ) fruiting bodies using a procedure that included 40% ammonium sulfate precipitation and DEAE-cellulose ion exchange chromatography, and designated GFAHP. This protein inhibited herpes simplex virus type 1 (HSV-1) replication in vitro with an IC50 value of 4.1 μg/ml and a...

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[#2007-04] Effect of various natural products on growth of bladder cancer cells: two promising mushroom extracts, Sensuke Konno

Effect of various natural products on growth of bladder cancer cells: two promising mushroom extracts. Konno S New York Medical College; Department of Urology, Valhalla, NY Despite the availability of several therapeutic options, a safer and more effective modality is urgently needed for treatment of bladder cancer. Specific immunotherapy is effective, but severe side effects limit its clinical use and underscore the need for unconventional therapies using less toxic substances. Many natural substances are touted for their medicinal aspects...

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[#2007-03] Induction of apoptosis in SGC-7901 cells by polysaccharide-peptide GFPS1b from the cultured mycelia of Grifola frondosa GF9801., Feng-Jie Cui et al.

Induction of apoptosis in SGC-7901 cells by polysaccharide-peptide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Cui FJ(a), Li Y(c), Xu YY(d), Liu ZQ(e), Huang DM(a), Zhang ZC(a), Tao WY(b) a)Institute of Bioengineering, School of Food and Biotechnology, Jiangsu University, b)Laboratory of Biopharmaceutics, School of Biotechnology, Southern Yangtze University, c)Department of Plant Science, North Dakota State University, Fargo, ND,d)Department of Cereal and Food Science, North Dakota State University, Fargo, ND, e)Institute of...

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