REFERENCES

[#2007-02] BIOACTIVE COMPOUNDS FROM MUSHROOMS, Hirokazu Kawagishi et al.

BIOACTIVE COMPOUNDS FROM MUSHROOMS Hirokazu Kawagishi and Cun Zhuang   Anti-dementia Compounds We have been engaged in a study to search for nerve growth factor (NGF) synthesis-promoting compounds in medicinal mushrooms,  since 1991. We discovered a series of benzyl alcohol derivatives named as hericenones C — H (1 - 6), as well as a series of diterpenoid derivatives named as erinacines A — 1 (7 -15) from Hericium erinaceum, which evidently stimulate NGF production from mouse astroglial...

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[#2007-01] Coriolus Abascal, Kathy et al. A Turkey Tail Polysaccharide as an Immunochemotherapy Agent in Cancer, Kathy Abascal et al.

A Turkey Tails Polysaccharide as an Immunochemotherapy Agent in Cancer Kathy Abascal, B.S., J.D., R.H. (AHG), and Eric Yarnell, N.D., R.H. (AHG) Abstract Trametes versicolor or Coriolus versicolor (turkey tails) is a medic­inal mushroom containing a number of protein-bound polysaccharides that have shown strong potential in the treatment of cancer. This discussion examines the use of Polysaccha­ride Krestin (PSK), a proprietary polysaccharide extracted from T. versicolor, in the treatment of gastric, colorectal, lung, breast, and esophageal...

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[#2006-08] Reishi: Pillai, Thulasi G. et al ‘The Radioprotective Properties’

Prevention of radiation-induced damages by aqueous extract of Ganoderma lucidum occurring in southern parts of India Thulasi G. Pillai1, Veena P. Salvi2, Dharmendra Kumar Maurya2,Cherupally Krishnan Krishnan Nair2 and K. K. Janardhanan1,* 1Amala Cancer Research Centre, Thrissur 680 555, India 2Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Mumbai 400 085, India Our previous studies have demonstrated that aqueous extract of Reishi (Ganoderma lucidum) occurring in South India possessed significant antioxidant...

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[#2006-07] Meshima: Kojima, Hiroyuki et al ‘Antitumor’

A Case of Spontaneous Regression of Hepatocellular Carcinoma with Multiple Lung Metastases Hiroyuki Kojima, Noboru Tanigawa, Shuji Kariya, Atsushi Komemushi, Yuzo Shomura, Satoshi Sawada, Eitatsu Arai, and Yoshiro Yokota Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. We present herein the case of a patient with hepatocellular carcinoma with multiple lung metastases in whom malignancy spontaneously regressed after taking Meshima (Phellinus linteus Mycelium). A 79­year-old man consulted our hospital complaining...

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[#2006-06] Immunomodulatory Properties of Grifola frondosa in Submerged Culture, Ming-Jiuan Wu et al.

Immunomodulatory Properties of Grifola frondosa in Submerged Culture Wu MJ(a), Cheng TL(b), Cheng SY(a), Lian TW(a), Wang LS(c), Chiou SY(d) a)Department of Biotechnology, Chia-Nan University of Pharmacy and Science, b)Taiwan Sugar Research Institute, c)Cheng-Kung University, d)Department of Health and Nutrition, Taiwan Maitake (Grifola frondosa) is a popular mushroom in Asia for its tasty flavor and immune- stimulating property. The aim of the study is to investigate the innate immunity augmentation effects of different extracts of mycelia...

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[#2006-05] Lysophosphatidylethanolamine in Grifola frondosa as a neurotrophic activator via activation of MAP kinase, Atsuyoshi Nishina et al.

Lysophosphatidylethanolamine in Grifola frondosa as a neurotrophic activator via activation of  MAP kinase Atsuyoshi Nishina, Hirokazu Kimura, Akihiro Sekiguchi, Ryo-hei Fukumoto, Satoshi Nakajima and Shoei Furukawa ABSTRACT We found that Maitake (Grifola frondosa) extracts induced activation of mitogen-activated protein kinase (MAPK) in cultured PC12 cells, a cell line of rat pheochromocytoma cells. The active substance was isolated by a few chromatographic steps including high-performance liquid chromatography, and was identified to be...

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[#2006-04] Macrophage J774.1 cell is activated by MZ-Fraction (Klasma-MZ) polysaccharide in Grifola frondosa, Yuki Masuda et al.

Macrophage J774.1 cell is activated by MZ-Fraction (Klasma-MZ) polysaccharide in Grifola frondosa Masuda Y, Kodama N, Nanba H Department of Microbial Chemistry, Kobe Pharmaceutical University We previously reported that the (β-1,3)-branched (β-1,6)-glucan, MD-Fraction extracted from the fruit body of the edible maitake mushroom (Grifola frondosa) exhibits an antitumor effect. In this study, we separated a new polysaccharide from maitake, which we named Maitake MZ-Fraction (Klasma-MZ). MZ-Fraction is a β-glucan with a low molecular weight of...

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[#2006-03] Maitake Miyake, Naomi et al. Low molecular weight maitake MD-Fraction (Klasma-MD) hydrolyzed with endo-β-1,6-glucanase of Trichoderma harzianum induces antitumor activities

Low molecular weight maitake MD-Fraction (Klasma-MD) hydrolyzed with endo-β-1,6-glucanase of Trichoderma harzianum induces antitumor activities Miyake N, Masuda Y, Murata Y, Inoue M, Matuda K, Okamoto K, Nanba H, Kodama N Department of Microbial Chemistry, Kobe Pharmaceutical University We previously reported that MD-Fraction (Klasma-MD), a specific-structured β-glucan extracted from fruit bodies of maitake mushrooms (Grifola frondosa), can activate cellular immune systems and express antitumor effects. The molecular weight of the...

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[#2006-02] Maitake Gu, Chang-Qing et al. Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-α in HepG2 2.2.15

Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-α in HepG2 2.2.15 Gu CQ, Li JW, Chao FH Institute of Health and Environmental Medicine, PR China In this study, D-fraction extracted from Grifola frondosa ( GF-D from maitake ) and its combination with human interferon alpha-2b (IFN) were investigated for the inhibitory effect on hepatitis B virus (HBV) in HepG2 2.2.15 cells (2.2.15 cells). HBV DNA and viral antigens were analyzed by a quantitative real-time polymerase chain...

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[#2006-01] Lion’s Mane Nagai, Kaoru et al Dilinoleoyl-phosphatidylethanolamine from Hericium erinaceum protects against ER stress-dependent Neuronal cell death via protein kinase C pathway

Dilinoleoyl-phosphatidylethanolamine from Hericium erinaceum protects against ER stress-dependent Neuronal cell death via protein kinase C pathway Kaoru Nagai a,*, Akiko Chibab, Toru Nishinoa, Takeo Kubotaa, Hirokazu Kawagishib,* aDepartment of Epigenetic Medicine, Interdisciplinary Graduate School ofMedicine and Engineering, University of Yamanashi, Yamanashi 409-3898, Japan bDepartment of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Shizuoka 422-8529, Japan Abstract In many types of neurodegeneration, neuronal...

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